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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CCR4 Antibody (aa8‑26) LS‑C12624
Note: This antibody replaces LS-C21427, LS-C21399
CCR4 antibody LS-C12624 is an unconjugated goat polyclonal antibody to mouse CCR4. Validated for ELISA, Flow, IHC and WB.
Antibody
Catalog
Size
Price
LS-C12624-100
100 µg (1 mg/ml)
$530

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Antibody
Species: Mouse
Applications: IHC, IHC - Frozen, Western blot, Flow Cytometry, ELISA

Product Description

CCR4 antibody LS-C12624 is an unconjugated goat polyclonal antibody to mouse CCR4. Validated for ELISA, Flow, IHC and WB.

Specifications

Target
Mouse CCR4
Synonyms
CCR4, C-C chemokine receptor type 4, CD194, CD194 antigen, C-C CKR-4, Chemr13, CKR-4, CC chemokine receptor 4, CC-CKR-4, CCR-4, HGCN:14099, C-c chemokine receptor 4, Chemokine (C-C) receptor 4, CKR4, CMKBR4, K5-5
Host
Goat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Applications
  • IHC (1:250)
  • Western blot (1:500)
  • Flow Cytometry
  • ELISA (1:25000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
CCR4 antibody was raised against synthetic peptide DTTQDETVYNSYYFYESMPC corresponds to amino acid residues 8-26 of mouse CC chemokine receptor CCR4. Percent identity by BLAST analysis: Mouse (100%).
Epitope
aa8-26
Specificity
Recognizes mouse CCR4. No cross-reactivity to human CCR4. Species sequence homology: other human chemokine receptors ~50%.
Usage
Suitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistochemistry. ELISA: 1:25000. Western Blot: 1:500. Immunohistochemistry: 1:250. Flow Cytometry: 1-3 ul Labels 1E6 cells in 50-100ul.
Presentation
PBS, pH 7.2, 1 mg/ml BSA, 0.09% sodium azide
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About CCR4
High affinity receptor for the C-C type chemokines CCL17/TARC and CCL22/MDC. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival. P51679 NM_005508 NP_005499.1


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Requested From: United States
Date Requested: 10/19/2018

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