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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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CBX3 / HP1 Gamma Antibody LS‑C24211
Antibody
HP1 Gamma antibody LS-C24211 is an unconjugated rat monoclonal antibody to mouse HP1 Gamma (CBX3). Validated for ELISA, IHC and WB.
Catalog
Size
Price
LS-C24211-2000
2000 µl
Unavailable

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Product Description

HP1 Gamma antibody LS-C24211 is an unconjugated rat monoclonal antibody to mouse HP1 Gamma (CBX3). Validated for ELISA, IHC and WB.
About CBX3 / HP1 Gamma
Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Q13185 NM_016587 NP_057671.2

CBX3 Antibody, Chromobox homolog 3 Antibody, HP1Hs-gamma Antibody, Heterochromatin-like protein 1 Antibody, Modifier 2 protein Antibody, HP1-GAMMA Antibody, Chromobox protein homolog 3 Antibody, HECH Antibody, HP1 gamma Antibody, HP1 gamma homolog Antibody


Specifications

Target
Mouse CBX3 / HP1 Gamma
Host
Rat
Reactivity
Mouse (tested or 100% immunogen sequence identity)
Clonality
IgM Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
Full length M32 GST fusion protein.
Specificity
Recognizes the M32 molecule in mouse and the HP1 HS gamma molecule in man. 3H2612 has also been reported for use in Western blotting and recognizes a 22kD protein in mouse nuclear extracts. Shown to be distributed in a fine grain pattern within interphase nuclei. Species cross-reactivity: Mouse, human.
Usage
Suitable for use in ELISA, Immunohistochemistry (frozen), Western Blot. Western Blot: Reported.
Presentation
Tissue Culture Supernatant. Supplied as a liquid, 0.1% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/23/2018

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