Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC, Immunofluorescence, Western blot, Immunoprecipitation, ELISA
Mouse CBX1 / HP1 Beta
Mouse, Human (tested or 100% immunogen sequence identity)
IHC (1:250 - 1:2500)
Immunofluorescence (1:250 - 1:2500)
Western blot (1:250 - 1:2500)
Immunoprecipitation (1:250 - 1:2500)
ELISA (1:250 - 1:2500)
Specificity and Use
CBX1 / HP1 Beta antibody was raised against recombinant mouse HP1b.
Recognizes mouse Heterochromatin protein-1 beta (HP1b). Species cross-reactivity: human.
Suitable for use in Immunofluorescence, ELISA, Western Blot, Immunoprecipitation and Immunohistochemistry. Immunofluorescence: 1:250-1:2500. ELISA: 1:250-1:2500. Western Blot: 1:250-1:2500. Immunohistochemistry: 1:250-1:2500. Immunoprecipitation: 1:250-1:2500.
40% glycerol. No preservative added.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
CBX1 / HP1 Beta is a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins.