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Anti-CASR/Calcium Sensing Receptor Antibody (C-Terminus) LS-C4297

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Rabbit Polyclonal (IgG) to Human CASR/Calcium Sensing Receptor
Human
IHC, Western blot, ELISA
Unconjugated

Details

Human CASR/Calcium Sensing Receptor
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Antiserum

Applications

IHC, Western blot (1:1000 - 1:5000), ELISA (1:10000 - 1:50000)

Specificity and Use

CASR/Calcium Sensing Receptor antibody was raised against synthetic peptide consisting of 20aa sequence near the C-terminus of human CaSR (KLH).
C-Terminus
Recognizes human CaSR. No significant sequence homology with other GPCR. Species sequence Homology: Mouse/rat: 90%; bovine: 85%.
Suitable for use in ELISA, Western Blot and Immunohistochemistry. Immunohistochemistry: Formaldehyde fixed tissue.

Packaging

Neat serum, 0.1% sodium azide, 40% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CASR/Calcium Sensing Receptor

P41180 NM_000388 NP_000379.2

CASR Antibody, Ca sensing receptor Antibody, Ca2+ sensing receptor Antibody, Calcium-sensing receptor Antibody, FIH Antibody, EIG8 Antibody, GPRC2A Antibody, HHC Antibody, HHC1 Antibody, Hypocalciuric hypercalcemia 1 Antibody, PCAR1 Antibody, NSHPT Antibody, CAR Antibody, FHH Antibody

CASR, a Calcium-Sensing Receptor, functions as a sensor in parathyroid and kidney to determine extracellular calcium concentration and to maintain calcium homeostasis. This receptor regulates both secretion of parathyroid hormone and excretion of urinary calcium. Mutations that inactivate CASR cause familial hypocalciuric hypercalcemia, which is also correlated with hyperparathyroidism. On the other hand, mutations that activate CASR cause autosomal dominant hypocalcemia. Hjalm et al.

Requested From: United States
Date Requested: 9/29/2016

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