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Anti-CACNG2 / Stargazin Antibody (aa305-323) LS-C10353

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Wt. Vol. Conc. Price
100 µg - - $590
Inquire for larger quantities

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Rabbit Polyclonal (IgG) to Rat CACNG2 / Stargazin
Rat, Mouse, Hamster
Western blot, Immunoprecipitation
Unconjugated

Details

Rat CACNG2 / Stargazin
Rabbit
Rat, Mouse, Hamster (tested or 100% immunogen sequence identity)
IgG Polyclonal
Protein A purified

Applications

Western blot (0.5 - 2 µg/ml), Immunoprecipitation

Specificity and Use

CACNG2 / Stargazin antibody was raised against kLH-conjugated, synthetic peptide corresponding to amino acids 305-323 (KDSKDSLHANTANRRTTPV) of rat Stargazin. Percent identity by BLAST analysis: Mouse, Rat, Hamster (100%); Human, Gorilla, Gibbon, Monkey, Marmoset, Panda, Bovine, Dog, Bat, Horse, Pig, Platypus, Xenopus (84%).
aa305-323
Recognizes Stargazin, Mr 36-39kD. Species cross-reactivity: Rat. Predicted to cross-react with mouse based on sequence homology.
Suitable for use in Western Blot and Immunoprecipitation. Western Blot: 0.5-2.0 ug/ml detects Stargazin in RIPA lysates from rat brain microsomal preparation. Rat brain microsomal preparation was resolved by electrophoresis, transferred to nitrocellulose and probed with anti-Stargazin (0.5 ug/ml). Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: 2-5 ug has been reported by an independent laboratory to immunoprecipitate Stargazin in rat P2 lysate.

Packaging

0.1 M Tris-glycine, pH 7.4, 0.15 M sodium chloride, 0.05% sodium azide, 30% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About CACNG2 / Stargazin

Q9Y698 NM_006078 NP_006069.1

CACNG2 Antibody, MRD10 Antibody, TARP gamma-2 Antibody, Waggler Antibody, Gamma2 Antibody, Stargazin Antibody

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.

Requested From: United States
Date Requested: 10/1/2016

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