Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
IHC - Frozen, Immunoprecipitation, Flow Cytometry (applications tested for the base form of this product only)
Chicken, Quail (tested or 100% immunogen sequence identity)
Also available conjugated with FITC, RPE.
Protein G purified
IHC - Frozen
Flow Cytometry (1:200 - 1:1000)
(applications tested for the base form of this product only)
Specificity and Use
Bu-1a antibody was raised against chicken Bursa cells.
Recognizes the a allele of the polymorphic cell surface antigen Bu-1. Bu-1a is a 70kD alloantigen expressed on B cells and a subset of macrophages. Reports suggest that Bu-1 is expressed on B cell precursors at early stages of development. Weak cross-reactivity with Bu-1b may be seen at higher antibody levels. This may be removed by appropriate titration.
Flow Cytometry: Use 10 ul of the suggested working dilution to label 10^6 cells in 100 ul. Method sheets are available on request.