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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BTRCP / BETA‑TRCP Antibody LS‑C39733 Best Seller
BETA-TRCP antibody LS-C39733 is an unconjugated mouse monoclonal antibody to human BETA-TRCP (BTRCP). Validated for ELISA, IP and WB.
Catalog
Size
Price
LS-C39733-100
100 µg (0.5 mg/ml)
Unavailable

Popular BTRCP / BETA-TRCP Products

BTRC / bTrCP antibody LS-C145640 Western blot of Mouse Pancreas lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Mouse, Human, Monkey, Rat, Bovine, Dog, Guinea pig, Pig, Rabbit
Applications: Western blot
Immunohistochemistry of paraffin-embedded human stomach tissue.
Species: Human, Mouse, Rat
Applications: IHC, Immunofluorescence, Western blot
Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Species: Rat, Human, Monkey, Mouse, Bovine, Dog, Horse, Pig, Rabbit, Xenopus
Applications: IHC, IHC - Paraffin, Western blot
Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using BTRC mouse mAb with DAB staining.
Species: Human
Applications: IHC, Western blot, Flow Cytometry, ELISA

Product Description

BETA-TRCP antibody LS-C39733 is an unconjugated mouse monoclonal antibody to human BETA-TRCP (BTRCP). Validated for ELISA, IP and WB.
About BTRCP / BETA-TRCP
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes and binds to phosphorylated target proteins. SCF(BTRC) mediates the ubiquitination of CTNNB1 and participates in Wnt signaling. Q9Y297 NM_003939 NP_003930.1

BTRC Antibody, BETA-TRCP Antibody, Beta-TrCP1 Antibody, BTrCP Antibody, BetaTrCP Antibody, E3RSIkappaB Antibody, FBW1A Antibody, F-box and WD-repeat protein 1B Antibody, FBXW1 Antibody, FWD1 Antibody, BTrCP1 Antibody, FBXW1A Antibody


Specifications

Target
Human BTRCP / BETA-TRCP
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1,k Monoclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • Western blot (1 - 3 µg/ml)
  • Immunoprecipitation
  • ELISA (0.1 - 1 µg/ml)
  • (applications tested for the base form of this product only)
Immunogen
Recombinant human beta-TrCP fusion protein.
Specificity
Recognizes the ~70kD human beta-TrCP. Does not exhibit cross reactivity with other proteins in Western blot applications. Reactivity has been confirmed with human beta-TrCP-transfected HEK293 cell lysates.
Usage
Suitable for use in Western Blot, Immunoprecipitation and ELISA. Western Blot: 1-3 ug/ml. Immunoprecipitation: 7 ug/IP reaction. ELISA: 0.1-1 ug/ml.
Presentation
PBS, pH 7.4, 0.1% sodium azide.
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Images


Western blot

Western blot of HEK 293 cells transfected with b-TrCP
Western blot of HEK 293 cells transfected with b-TrCP

Western blot

Western blot of HEK 293 cells transfected with b-TrCP
Western blot of HEK 293 cells transfected with b-TrCP

Western blot

Western blot of HEK 293 cells transfected with b-TrCP
Western blot of HEK 293 cells transfected with b-TrCP

Western blot

Western blot of HEK 293 cells transfected with b-TrCP
Western blot of HEK 293 cells transfected with b-TrCP


Requested From: 
Date Requested: 6/19/2018

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