The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|BST2 antibody was raised against synthetic peptide C-ELTEAQKGFQD from an internal region of human BST2 (NP_004326.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon (100%).|
|Peptide ELISA: antibody detection limit dilution 1:32000. Western blot: Approx 30kDa band observed in Human Spleen and Testis lysates (calculated MW of 19.8kDa according to NP_004326.1). The observed molecular weight corresponds to earlier findings in literature with different antibodies (Rollason, J Cell Sci. 2007 Nov 1;120(Pt 21):3850-8.; PMID: 17940069). Recommended concentration: 1-3 ug/ml.|
|Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide|
|Store at -20°C. Minimize freezing and thawing.|
|For research use only.|
BST2 Antibody, Bone marrow stromal antigen 2 Antibody, BST-2 Antibody, CD317 antigen Antibody, CD317 Antibody, HM1.24 antigen Antibody, NPC-A-7 Antibody, TETHERIN AntibodyIFN-induced antiviral host restriction factor which efficiently blocks the release of diverse mammalian enveloped viruses by directly tethering nascent virions to the membranes of infected cells. Acts as a direct physical tether, holding virions to the cell membrane and linking virions to each other. The tethered virions can be internalized by endocytosis and subsequently degraded or they can remain on the cell surface. In either case, their spread as cell-free virions is restricted.