Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
Bovine (at least 90% immunogen sequence identity)
Western blot (1:1000) & (1 - 3 µg/ml)
Specificity and Use
BRUNOL5 / CELF5 antibody was raised against synthetic peptide C-EPPGGQPDGMKD from an internal region (near the N-terminus) of human CELF5 / BRUNOL5 (NP_068757.2). Percent identity by BLAST analysis: Human, Panda (100%); Bovine (92%).
LS-E26470 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54595. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
CELF5 Antibody, Brunol5 Antibody, CELF-5 Antibody, Bruno-like protein 5 Antibody, CUG-BP and ETR-3 like factor 5 Antibody, BRUNOL-5 Antibody, RNA-binding protein BRUNOL-5 Antibody
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.