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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BRUCE / BIRC6 Antibody (aa37‑52) LS‑C2965
Antibody
BIRC6 antibody LS-C2965 is an unconjugated rabbit polyclonal antibody to BIRC6 (BRUCE) from human, mouse, monkey and other species. Validated for ELISA.
Catalog
Size
Price
LS-C2965-100
100 µg
Unavailable

Popular BRUCE / BIRC6 Products

Anti-BIRC6 antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4702 concentration 5 ug/ml.
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Anti-BRUCE / BIRC6 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8292 dilution 3.75 ug/ml.
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Detection of Human BIRC6/Apollon by Immunohistochemistry. Sample: FFPE section of human metastatic lymph node. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of 1:250.
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Detection of Human BIRC6/Apollon by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-BIRC6/Apollon used at a dilution of 1:5000 (0.2 ug/ml).
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Immunohistochemistry of Human cervical cancer using BIRC6 Polyclonal Antibody at dilution of 1:7.
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Product Description

BIRC6 antibody LS-C2965 is an unconjugated rabbit polyclonal antibody to BIRC6 (BRUCE) from human, mouse, monkey and other species. Validated for ELISA.
About BRUCE / BIRC6
Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Q9NR09 NM_016252 NP_057336.3

BIRC6 Antibody, APOLLON Antibody, BRUCE Antibody, KIAA1289 Antibody


Specifications

Target
Human BRUCE / BIRC6
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rabbit (tested or 100% immunogen sequence identity)
Predicted
Bat (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Applications
  • ELISA (1:1000)
Immunogen
BRUCE / BIRC6 antibody was raised against synthetic peptide from human BIRC6. Percent identity by BLAST analysis: Human, Gibbon, Monkey, Marmoset, Mouse, Elephant, Panda, Rabbit, Opossum (100%); Bat (94%); Horse (88%); Chicken, Stickleback, Pufferfish, Zebrafish (81%).
Epitope
aa37-52
Specificity
KLH conjugated synthetic peptide comprising amino acids 37 - 52 [CDADGLHSLSYHPALN] of the human baculoviral IAP repeat-containing 6 (BIRC6) protein.
Presentation
PBS, 0.09% sodium azide.
Storage
Lyophilized and resuspended forms: store at -20°C.
Restrictions
For research use only.
Guarantee
This antibody carries the LSBio 100% Guarantee.

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Requested From: 
Date Requested: 6/18/2018

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