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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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BLM Antibody LS‑C4190
BLM antibody LS-C4190 is an unconjugated rabbit polyclonal antibody to human BLM. Validated for IHC, IP and WB.
Antibody
Catalog
Size
Price
LS-C4190-50
50 µg
$575

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Product Description

BLM antibody LS-C4190 is an unconjugated rabbit polyclonal antibody to human BLM. Validated for IHC, IP and WB.
About BLM
Participates in DNA replication and repair. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction. Involved in 5'-end resection of DNA during double-strand break (DSB) repair: unwinds DNA and recruits DNA2 which mediates the cleavage of 5'-ssDNA. Negatively regulates sister chromatid exchange (SCE). P54132 NM_000057 NP_000048.1

BLM Antibody, Bloom syndrome Antibody, Bloom syndrome protein Antibody, BS Antibody, Bloom's syndrome protein Antibody, DNA helicase, RecQ-like type 2 Antibody, RECQ2 Antibody, RECQL2 Antibody, RECQL3 Antibody, RecQ protein-like 3 Antibody


Specifications

Target
Human BLM
Host
Rabbit
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Affinity purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot (1:1000 - 1:10000)
  • Immunoprecipitation
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
BLM antibody was raised against synthetic peptide corresponding to a region of human BLM encoded within exon 22.
Specificity
Specific for human Bloom Syndrome (BLM).
Usage
Suitable for use in Western Blot. Immunoprecipitation and Immunohistochemistry (Frozen). Western Blot: 1:1000-1:10000. Immunoprecipitation:1-4 ug/mg protein.
Presentation
Tris-citrate/phosphate, pH 7.4, 0.02% sodium azide.
Storage
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
Restrictions
For research use only.

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Requested From: United States
Date Requested: 9/22/2018

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