Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Rat Monoclonal (IgG1) to Mouse Basigin / Emmprin / CD147
IHC - Paraffin, IHC - Frozen, Western blot, Flow Cytometry
Mouse Monoclonal (IgG1) to Human Basigin / Emmprin / CD147
Human Basigin / Emmprin / CD147
Human (tested or 100% immunogen sequence identity)
Protein G purified
Specificity and Use
Recognizes a 50-60kD type I single chain transmembrane glycoprotein named basigin or neurothelin which is a blood-brain barrier-specific molecule.
Suitable for use in flow cytometric analysis using 100 ul peripheral blood cells or 20 ul/1E6 cells. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.
PBS, pH 7.2, 0.1% sodium azide.
Short term: +4°C; Long term: Add glycerol (40-50%) -20°C.
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.