Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Detects endogenous levels of proteins containing the phospho-(Ser/Thr) ATM/ATR substrate motif. Preferentially binds peptides/proteins that contain phospho-Ser/Thr preceded by Leu or similar hydrophobic amino acids at the -1 position and followed by Gln at the +1 position. No cross-reactivity is observed with corresponding non-phosphorylated sequences or with other phospho-Ser/Thr-containing motifs. Species cross-reactivity: All species.
Suitable for use in ELISA, Western Blot, Immunoprecipitation, Immunocytochemistry and Immunohistochemistry. Western Blot: 1:1000. Immunoprecipitation: 1:20. ELISA: 1:1000. Immunohistochemistry (paraffin): 1:100.
10 mM sodium HEPES, pH 7.5, 150 mM sodium chloride, 0.1 mg/ml BSA, 50% glycerol.
Long term: -20°C; Short term: +4°C. Avoid repeat freeze-thaw cycles.