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Anti-ATG4A Antibody (aa2-398) LS-C34999

Catalog Size Price
LS-C34999-100 100 µg Unavailable

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25 ATG4A Antibodies

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100% Guaranteed
Sheep Polyclonal (IgG) to Human ATG4A
Human
Western blot, ELISA
Unconjugated

Details

Human ATG4A
Sheep
Human (tested or 100% immunogen sequence identity)
IgG Polyclonal
Unconjugated
Affinity purified
Unmodified

Applications

  • Western blot (0.1 - 0.2 µg/ml)
  • ELISA (0.5 - 1 µg/ml)

Specificity and Use

ATG4A antibody was raised against sf21-derived, recombinant human Autophagy related protein 4 homolog A isoform 1 (aa2-398) Accession # Q8WYN0.
aa2-398
Recognizes human ATG4A.
Suitable for use in Western Blot and ELISA. Western Blot: 0.1-0.2 ug/ml. ELISA: 0.5-1 ug/ml.

Packaging

Lyophilized.
100 µl deionized water
For research use only.

About ATG4A

Q8WYN0 NM_052936 Q8WYN0

ATG4A Antibody, AUTL2 Antibody, Autophagin-2 Antibody, APG4A Antibody, Autophagin 2 Antibody, Cysteine protease ATG4A Antibody, HAPG4A Antibody, APG4 autophagy 4 homolog A Antibody

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Requested From: 
Date Requested: 5/24/2018

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