Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
TCR Screening Services
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
Human (tested or 100% immunogen sequence identity)
IHC - Paraffin
Specificity and Use
Astrocytes antibody was raised against human cerebral white matter from a multiple sclerosis patient.
Recognizes an intracellular protein antigen (MW 30kD) expressed by human and rat astrocytes and other specialized glia (Muller cells of the retina, Bergmann fibers of the cerebellar cortex, tanycytes of the hypothalamus and ciliated ependymal cells) in the central nervous system (CNS). The antibody has recently been found to be a specific marker for low grade astrocytoma in human brain tissue and is able to distinguish between low grade astrocytoma and normal reactive gliosis (patent application filed).
Suitable for use in Western Blot, Immunohistochemistry, Immunocytochemistry. Immunohistochemistry The antibody works on paraffin embedded tissue sections.