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Anti-ARHGEF4 Antibody (aa2-14) LS-C54531

Catalog Size Price
LS-C54531-100 100 µg (0.5 mg/ml) Unavailable

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Anti-ARHGEF4 Antibody (aa2-14) LS-C54531
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100% Guaranteed
Goat Polyclonal to Human ARHGEF4
Western blot, ELISA


Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Immunoaffinity purified


  • Western blot (2 - 4 µg/ml)
  • ELISA (1:32000)

  • IHC - Paraffin

Specificity and Use

ARHGEF4 antibody was raised against synthetic peptide PWEEPAGEKPSCS from the N-terminus of human ARHGEF4 (NP_056135.2; NP_127462.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (92%); Marmoset (85%).
LS-E25604 - Lyophilized - 100 µg - $145.00
Immunizing peptide used to generate LS-C54531. Useful for pre-absorption and neutralization of the antibody's antigen binding site.
Human ARHGEF4. This antibody is expected to recognise both reported isoforms (NP_056135.2; NP_127462.1).


Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Avoid freeze-thaw cycles.
For research use only.


Q9NR80 NM_015320 NP_056135.2

ARHGEF4 Antibody, ASEF1 Antibody, ASEF Antibody, GEF4 Antibody, KIAA1112 Antibody, STM6 Antibody

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Western blot

Western blot
HEK293 overexpressing ARHGEF4 (RC215591) and probed with the antibody (mock transfection in first lane).

Western blot

Western blot
Antibody (2 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: 
Date Requested: 3/20/2018

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