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Anti-ARHGEF4 Antibody (aa2-14) LS-C54531

Ordering

Wt. Vol. Conc. Price
100 µg - 0.5 mg/ml $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ARHGEF4 Antibodies

Anti-ARHGEF4 Antibody (aa573-599, APC) LS-C232821
Rabbit Polyclonal (IgG) to Human ARHGEF4
Human
Western blot, ELISA
APC Conjugated
Anti-ARHGEF4 Antibody (aa573-599, Biotin) LS-C232822
Rabbit Polyclonal (IgG) to Human ARHGEF4
Human
Western blot, ELISA
Biotin Conjugated
Anti-ARHGEF4 Antibody (aa573-599, PE) LS-C232824
Rabbit Polyclonal (IgG) to Human ARHGEF4
Human
Western blot, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Goat Polyclonal to Human ARHGEF4
Human
Western blot, ELISA
Unconjugated

Details

Human ARHGEF4
Goat
Human (tested or 100% immunogen sequence identity)
Monkey (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated
Immunoaffinity purified
Unmodified

Applications

  • Western blot (2 - 4 µg/ml)
  • ELISA (1:32000)

  • IHC - Paraffin

Specificity and Use

ARHGEF4 antibody was raised against synthetic peptide PWEEPAGEKPSCS from the N-terminus of human ARHGEF4 (NP_056135.2; NP_127462.1). Percent identity by BLAST analysis: Human, Gorilla (100%); Monkey (92%); Marmoset (85%).
LS-E25604 - Lyophilized - 100 µg - $145.00
aa2-14
Human ARHGEF4. This antibody is expected to recognise both reported isoforms (NP_056135.2; NP_127462.1).

Packaging

Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide
Store at -20°C. Minimize freezing and thawing.
For research use only.

About ARHGEF4

Q9NR80 NM_015320 NP_056135.2

ARHGEF4 Antibody, ASEF1 Antibody, ASEF Antibody, GEF4 Antibody, KIAA1112 Antibody, STM6 Antibody

Acts as guanine nucleotide exchange factor (GEF) for RHOA, RAC1 and CDC42 GTPases. Binding of APC may activate RAC1 GEF activity. The APC-ARHGEF4 complex seems to be involved in cell migration as well as in E-cadherin-mediated cell-cell adhesion. Required for MMP9 up-regulation via the JNK signaling pathway in colorectal tumor cells. Involved in tumor angiogenesis and may play a role in intestinal adenoma formation and tumor progression.

Western blot

Western blot
HEK293 overexpressing ARHGEF4 (RC215591) and probed with the antibody (mock transfection in first lane).

Western blot

Western blot
Antibody (2 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Requested From: United States
Date Requested: 12/4/2016

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