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Anti-ARHGEF1 Antibody (aa230-279) LS-C151517

Ordering

Wt. Vol. Conc. Price
50 µg - 1 mg/ml $365
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
Orders@LSBio.com
 

Most Popular ARHGEF1 Antibodies

Anti-ARHGEF1 Antibody (aa164-192, AP) LS-C251657
Rabbit Polyclonal (IgG) to Human ARHGEF1
Human
Western blot, ELISA
AP Conjugated
Anti-ARHGEF1 Antibody (aa164-192, Biotin) LS-C251661
Rabbit Polyclonal (IgG) to Human ARHGEF1
Human
Western blot, ELISA
Biotin Conjugated
Anti-ARHGEF1 Antibody (aa164-192, PE) LS-C251664
Rabbit Polyclonal (IgG) to Human ARHGEF1
Human
Western blot, ELISA
PE Conjugated

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human ARHGEF1
Human
Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human ARHGEF1
Rabbit
Human (tested or 100% immunogen sequence identity)
Mouse, Rat, Bat, Bovine, Dog (at least 90% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Biotin, FITC, HRP.
Immunoaffinity purified
Unmodified

Applications

  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

ARHGEF1 antibody was raised against synthetic peptide located between aa230-279 of human ARHGEF1 (Q92888, NP_945353). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon (100%); Galago, Mouse, Rat, Dog, Bovine, Bat (92%); Panda, Horse, Pig (85%); Elephant (84%).
LS-E23093 - Lyophilized - 100 µg - $145.00
aa230-279
Human ARHGEF1

Packaging

Lyophilized from PBS with 2% sucrose
Distilled water
Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year); Short term (less than one week): +4°C. Avoid repeat freeze-thaw cycles.
For research use only.

About ARHGEF1

Q92888 NM_004706 NP_004697.2

ARHGEF1 Antibody, 115-kD protein Antibody, Arp2/3 complex 34 kd subunit Antibody, GEF1 Antibody, LBCL2 Antibody, p115RhoGEF Antibody, LSC Antibody, Lsc homolog Antibody, SUB1.5 Antibody, p115-RHOGEF Antibody

Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation.

Western blot

Western blot
ARHGEF1 antibody Western Blot of Jurkat. This image was taken for the unconjugated form of this product. Other forms have not been tested.
 

Requested From: United States
Date Requested: 12/7/2016

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