The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|APOBEC3C antibody was raised against synthetic peptide C-RLLKRRLRESLQ from the C-terminus of human APOBEC3C (NP_055323.2). Percent identity with other species by BLAST analysis: Human (100%), Monkey (83%).|
|Peptide ELISA: antibody detection limit dilution 1:1000. Western blot: Approx. 22 kDa band observed in lysates of cell line DAUDI (calculated MW of 22.8 kDa according to NP_055323.2). Recommended concentration: 0.5-1.5 ug/ml.|
|Tris-buffered saline, pH 7.3, 0.5% BSA, 0.02% sodium azide|
|Store at -20°C. Minimize freezing and thawing.|
|For research use only.|
APOBEC3C Antibody, A3C Antibody, APOBEC1-like Antibody, APOBEC1L Antibody, ARP5 Antibody, BK150C2.3 Antibody, Phorbolin i Antibody, ARDC2 Antibody, ARDC4 Antibody, PBI AntibodyDNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA.