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Anti-APEX2 Antibody IHC-plus™ LS-B2015

Note: This antibody replaces LS-C626


Wt. Vol. Conc. Price
- 50 µl - $395
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)

Most Popular APEX2 Antibodies

Anti-APEX2 Antibody IHC-plus™ LS-B2015
Rabbit Polyclonal (IgG) to Human APEX2
Human, Monkey, Bovine, Dog, Pig, Rabbit
IHC - Paraffin, Western blot
Immunohistochemistry Image
Anti-APEX2 Antibody (aa143-171, APC) LS-C275164
Rabbit Polyclonal (IgG) to Human APEX2
IHC, Western blot, ELISA
APC Conjugated
Anti-APEX2 Antibody (aa504-518) LS-C312651
Rabbit Polyclonal (IgG) to Human APEX2
Human, Monkey, Mouse, Rat, Bovine, Pig, Rabbit, Sheep
IHC - Paraffin, Western blot

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal (IgG) to Human APEX2
Human, Monkey, Bovine, Dog, Pig, Rabbit
IHC - Paraffin, Western blot


Human APEX2
Human, Monkey, Bovine, Dog, Pig, Rabbit (tested or 100% immunogen sequence identity)
Mouse, Rat (at least 90% immunogen sequence identity)
IgG Polyclonal
Protein G purified


  • IHC - Paraffin (10 µg/ml)
  • Western blot (1:500 - 1:1000)

Specificity and Use

APEX2 antibody was raised against this antibody was generated by immunizing rabbits with EELRALDSEGRALLTQHKI (aa122-140) andGQAKTSEAKDEKELRTSF (aa438-455) peptides of human APEXL2. Genbank accession no. NM_014481. Percent identity by BLAST analysis: Human, Gorilla, Monkey, Marmoset, Elephant, Panda, Dog, Bovine, Rabbit, Pig (100%); Mouse, Rat (95%); Hamster (89%).
In HeLa, a 54 kD band is observed.
Immunohistochemistry: LS-B2015 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2015 was determined to be 10 ug/ml.


PBS, 0.02% sodium azide.
Store at 4°C for short term applications. For long term storage, aliquot and store at -20°C.
For research use only.

About APEX2

Q9UBZ4 NM_014481 NP_055296.2

APEX2 Antibody, AP endonuclease 2 Antibody, AP endonuclease XTH2 Antibody, APEX nuclease 2 Antibody, APEX nuclease-like 2 Antibody, APEXL2 Antibody, APE2 Antibody, XTH2 Antibody

Function as a weak apurinic/apyrimidinic (AP) endodeoxyribonuclease in the DNA base excision repair (BER) pathway of DNA lesions induced by oxidative and alkylating agents. Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. Displays also double-stranded DNA 3'-5' exonuclease, 3'-phosphodiesterase activities.


Anti-APEX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2015 concentration 10 ug/ml.

Western blot

Western blot
Western blot of APEXL2 in HeLa cell lysates using antibody at a dilution of 1:500.

Requested From: United States
Date Requested: 10/24/2016

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