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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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AKAP6 / MAKAP Antibody (aa1666‑2319) LS‑C11830 Best Seller
MAKAP antibody LS-C11830 is an unconjugated rabbit polyclonal antibody to MAKAP (AKAP6) from human and rat. Validated for IHC, IP and WB.
Antibody
Catalog
Size
Price
LS-C11830-200
200 µg (1 mg/ml)
$590

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Species: Human, Rat
Applications: IHC, Western blot, Immunoprecipitation

Product Description

MAKAP antibody LS-C11830 is an unconjugated rabbit polyclonal antibody to MAKAP (AKAP6) from human and rat. Validated for IHC, IP and WB.

Specifications

Target
Human AKAP6 / MAKAP
Synonyms
AKAP6, ADAP100, A-kinase anchor protein 6, AKAP 100, AKAP-6, ADAP6, AKAP100, MAKAP, KIAA0311, PRKA6
Host
Rabbit
Reactivity
Human, Rat (tested or 100% immunogen sequence identity)
Clonality
IgG Polyclonal
Conjugations
Unconjugated. Also available conjugated with AP, APC, Biotin, FITC, HRP, PE.
Purification
Protein A purified
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • Western blot
  • Immunoprecipitation
  • (applications tested for the base form of this product only)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
AKAP6 / MAKAP antibody was raised against his-tagged, recombinant protein corresponding to residues 1666-2319 of human mAKAP (muscle AKAP).
Epitope
aa1666-2319
Specificity
Recognizes human mAKAP, Mr ~255kD, in skeletal muscle, ~300kD in brain and heart. Species cross-reactivity: rat.
Usage
Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Proteins were visualized using a goat anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system. Immunoprecipitation: 4 ug immunoprecipitated mAKAP from an L6 RIPA cell lysate. Immunohistochemistry: Has been shown to detect mAKAP in differentiated rat neonatal ventriculocytes and frozen rat heart tissue.
Presentation
PBS, pH 7.6, 0.07% Sodium Azide, 30% Glycerol
Storage
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About AKAP6 / MAKAP
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. Q13023 NM_004274 NP_004265.3


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Requested From: United States
Date Requested: 10/19/2018

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