Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to
worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting
immunostaining in relation to complex human pathologies.
Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding.
Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".
ADAM12, ADAM 12, MCMPMltna, MCMP, MLTN, Meltrin-alpha, MLTNA
(tested or 100% immunogen sequence identity)
Rat (at least 90% immunogen sequence identity)
Western blot (1:500 - 1:2000)
ADAM12 antibody was raised against 13 amino acid synthetic peptide from the C-terminus of the mouse ADAM-12 protein (HQVPRPSHNAYIK). Percent identity by BLAST analysis: Mouse (100%); Rat (92%); Hamster, Horse (85%).
Recognizes mouse ADAM 12. Cross-reactivity with other ADAM family members untested.
Suitable for use in Western Blot. Not recommended for Flow Cytometry. Western Blot: 1:500-1:2000; 5% nonfat milk in PBS for blocking. Do not dilute the primary antibody in milk; Simple TBS or PBS is recommended. Variable size on gel expected, as there are several processed forms of the protein.
No preservatives added
Short term: 4°C; Long term: Add glycerol (40-50%) -20°C.
ADAM12 is a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms.