ABCC5 / MRP5

ATP-binding cassette, sub-family C (CFTR/MRP), member 5

ABCC5 / MRP5 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions in the cellular export of its substrate, cyclic nucleotides. This export contributes to the degradation of phosphodiesterases and possibly an elimination pathway for cyclic nucleotides. Studies show that this protein provides resistance to thiopurine anticancer drugs, 6-mercatopurine and thioguanine, and the anti-HIV drug 9-(2-phosphonylmethoxyethyl)adenine. This protein may be involved in resistance to thiopurines in acute lymphoblastic leukemia and antiretroviral nucleoside analogs in HIV-infected patients. Alternative splicing of this gene has been detected; however, the complete sequence and translation initiation site is unclear.

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Products

Antibodies (46)

Proteins (5)

ELISA Kits (3)

Type

Over-Expression Lysate (2)

Primary (46)

Recombinant (3)

Sandwich (3)

Target

ABCC5 / MRP5 (54)

Reactivity

Human (48)

Mouse (8)

Rat (8)

Bovine (4)

Chicken (1)

Chimpanzee (3)

Dog (4)

Gibbon (3)

Horse (4)

Monkey (4)

Pig (4)

Rabbit (4)

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Application

IHC (17)

IHC-Fr (4)

IHC-P (3)

WB (40)

ELISA (16)

ICC (4)

IF (1)

Peptide-ELISA (2)

Host

rabbit (21)

mouse (18)

goat (1)

rabbit-new zealand white (2)

rat (4)

Product Group

IHCPlus (2)

Isotype

IgG (16)

IgG1 (10)

IgG2a (4)

IgG2a,k (6)

IgG2b (2)

Clonality

monoclonal mc (22)

polyclonal pc (24)

Clone

6C6 (2)

M5I-1 (1)

M5I-10 (2)

M5II-54 (1)

OTI1F3 (2)

OTI2C8 (2)

OTI4B1 (2)

OTI5A8 (2)

OTI5F4 (2)

Format

96-Well Microplate (1)

96-Well Strip Plate (2)

APC Conjugated (2)

Azide-free (1)

Biotin Conjugated (4)

Carrier-free (6)

Concentrated (3)

FITC Conjugated (4)

HRP Conjugated (4)

PE Conjugated (2)

Unconjugated (30)

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Epitope

aa631-661 (6)

aa131-180 (4)

aa1-38 (1)

aa10-60 (1)

aa2-13 (1)

aa500-550 (1)

aa760-846 (1)

Publications

No (53)

Yes (1)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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IHC-plus™ ABCC5 / MRP5 Antibody (aa2-13) LS-B2334

(5.0) Rating

(1) Publication(s)

Antibody:

ABCC5 / MRP5 Goat anti-Human Polyclonal (aa2-13) Antibody

Reactivity:

Chicken, Bovine, Rabbit, Dog, Pig, Horse, Human, Monkey

Applications:

IHC, IHC-P, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µg/$485

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IHC-plus™ ABCC5 / MRP5 Antibody (clone 6C6) LS-B13042

(4.0) Rating

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (6C6) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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ABCC5 / MRP5 Antibody (aa1-38, clone M5I-10) LS-C124153

Antibody:

ABCC5 / MRP5 Rat anti-Mouse Monoclonal (aa1-38) (M5I-10) Antibody

Reactivity:

Mouse

Applications:

ICC, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

1 ml/$836

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ABCC5 / MRP5 Antibody (clone M5II-54, Concentrated) LS-C202619

Antibody:

ABCC5 / MRP5 Rat anti-Human Monoclonal (Concentrated) (M5II-54) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-Fr, WB

Format:

Unconjugated, Concentrated

Price:

1 ml/$522

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ABCC5 / MRP5 Antibody (clone M5I-1, Concentrated) LS-C202618

Antibody:

ABCC5 / MRP5 Rat anti-Human Monoclonal (Concentrated) (M5I-1) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-Fr, WB

Format:

Unconjugated, Concentrated

Price:

1 ml/$522

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ABCC5 / MRP5 Antibody (clone M5I-10, Concentrated) LS-C202801

Antibody:

ABCC5 / MRP5 Rat anti-Human Monoclonal (Concentrated) (M5I-10) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-Fr, WB

Format:

Unconjugated, Concentrated

Price:

1 ml/$522

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ABCC5 / MRP5 Antibody LS-C806521

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ABCC5 / MRP5 Antibody (clone OTI2C8) LS-C798999

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (OTI2C8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

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ABCC5 / MRP5 Antibody (clone OTI2C8, Carrier-free) LS-C791665

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C8) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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ABCC5 / MRP5 Antibody LS-C402447

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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ABCC5 / MRP5 Antibody LS-C332329

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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ABCC5 / MRP5 Antibody LS-C671452

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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ABCC5 / MRP5 Antibody LS-C666862

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µg/$331

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ABCC5 / MRP5 Antibody LS-C747214

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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ABCC5 / MRP5 Antibody (aa760-846) LS-C309066

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (aa760-846) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$705

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ABCC5 / MRP5 Antibody (HRP) LS-C543239

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

100 µl/$904

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ABCC5 / MRP5 Antibody (Biotin) LS-C523107

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

100 µl/$904

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ABCC5 / MRP5 Antibody (FITC) LS-C533150

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

100 µl/$904

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ABCC5 / MRP5 Antibody (PE) LS-C651348

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

100 µl/$904

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ABCC5 / MRP5 Antibody (APC) LS-C514892

Antibody:

ABCC5 / MRP5 Mouse anti-Human Monoclonal (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

100 µl/$904

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • APC

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ABCC5 / MRP5 Antibody (aa500-550) LS-C829555

Antibody:

ABCC5 / MRP5 Rabbit-New Zealand White anti-Human Polyclonal (aa500-550) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

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ABCC5 / MRP5 Antibody (aa10-60) LS-C829434

Antibody:

ABCC5 / MRP5 Rabbit-New Zealand White anti-Human Polyclonal (aa10-60) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$393

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ABCC5 / MRP5 Antibody (aa631-661) LS-C327937

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal (aa631-661) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ABCC5 / MRP5 Antibody LS-C778605

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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ABCC5 / MRP5 Antibody LS-C832915

Antibody:

ABCC5 / MRP5 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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