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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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ABCC3 / MRP3 Antibody (aa830‑949) LS‑C16477 Best Seller
Note: This antibody replaces LS-C16476
MRP3 antibody LS-C16477 is an unconjugated mouse monoclonal antibody to human MRP3 (ABCC3). Validated for ELISA, Flow, ICC, IF, IHC and WB. Cited in 1 publication.
Antibody
Catalog
Size
Price
LS-C16477-250
250 µg (0.25 mg/ml)
$1,260

Popular ABCC3 / MRP3 Products

Antibody
Species: Human
Applications: IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry
Antibody
Species: Human
Applications: IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry
ABCC3 antibody immunohistochemistry of formalin-fixed and paraffin-embedded human colon carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Species: Human
Applications: IHC, IHC - Paraffin, Western blot, Flow Cytometry
ABCC3 / MRP3 antibody LS-C102044 Western blot of MCF7 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Species: Human, Dog, Guinea pig
Applications: Western blot

Product Description

MRP3 antibody LS-C16477 is an unconjugated mouse monoclonal antibody to human MRP3 (ABCC3). Validated for ELISA, Flow, ICC, IF, IHC and WB. Cited in 1 publication.

Specifications

Target
Human ABCC3 / MRP3
Synonyms
ABCC3, ABC31, EST90757, MOAT-D, MLP2, Multidrug resistance protein 3, MRP3, CMOAT2
Host
Mouse
Reactivity
Human (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Conjugations
Unconjugated
Purification
Tissue culture supernatant
Modifications
Unmodified
Applications
  • IHC
  • IHC - Frozen
  • ICC (1:20 - 1:50)
  • Immunofluorescence
  • Western blot (1:20 - 1:50)
  • Flow Cytometry
  • ELISA
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Immunogen
ABCC3 / MRP3 antibody was raised against recombinant human MRP3 (multidrug resistance-associated protein 3) (aa 830-949).
Epitope
aa830-949
Specificity
Recognizes an internal epitope of human MRP3. Does not cross-react with human P-glycoprotein, MDR3 P-glycoprotein, MRP1, MRP2 (cMOAT) or MRP5. Does not cross-react with mouse, rat or guinea pig MRP2.
Usage
Suitable for use in Immunofluorescence, Flow Cytometry, ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Flow Cytometry: Weak, cell permeabilization required. Western Blot: Use 1:20-1:50 and IgG (HRP) anti-mouse. Immunocytochemistry: 1:20-1:50 on acetone or formaldehyde fixed cytospin preparations. Immunohistochemistry (Frozen sections): 1:20 on acetone fixed frozen sections followed by incubation with IgG rabbit anti-mouse and a monoclonal mouse APAAP complex. Alternatively, after incubation with the primary antibody (1:20) and washing, slides can be incubated with IgG (Biotin) rabbit anti-mouse and Streptavidin (HRP).
Presentation
Tissue Culture Supernatant, 0.1% Sodium Azide, 0.7% BSA
Storage
Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only.
About ABCC3 / MRP3
ABCC3 / MRP3 is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. O15438 NM_003786 AAD02845.1


Publications (1)

1
Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. Kleberg K, Jensen GM, Christensen DP, Lundh M, Grunnet LG, Knuhtsen S, Poulsen SS, Hansen MB, Bindslev N. BMC gastroenterology. 2012 12:78. (IHC; Human) [Full Text Article] [PubMed:22734885] [PMC:PMC3457850]

Customer Reviews (0)


Requested From: United States
Date Requested: 10/21/2018

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