P Glycoprotein antibody LS-C11667 is an unconjugated mouse monoclonal antibody to human P Glycoprotein (ABCB1 / MDR1). Validated for Flow and IHC.
Human ABCB1 / MDR1 / P Glycoprotein
(tested or 100% immunogen sequence identity)
Tissue culture supernatant
- IHC - Paraffin (1:10 - 1:20)
- IHC - Frozen (1:10 - 1:20)
- Flow Cytometry
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including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Multi drug resistant Chinese hamster ovary cell line, CHrC5.
Recognizes the 170-180kD P-glycoprotein, a plasma membrane associated molecule which is important in mediating resistance to cytotoxic drugs. In normal tissues P-glycoprotein is expressed in liver, kidney, colon, adrenal gland and lung. In malignant conditions increased expression of P-glycoprotein may be associated with multi-drug resistance, and the detection of this can have important consequences for treatment. This clone has also been reported to be suitable for Western blot analysis.
Immunohistology: This product requires protein digestion pre-treatment of paraffin sections e. g. 0.1% pronase, 10 mins.
PBS, 0.09% Sodium Azide, 1% BSA
Store at 4°C or -20°C. Avoid freeze-thaw cycles.
For research use only.
About ABCB1 / MDR1 / P Glycoprotein