V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibodies

V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA)

NFKB1 or NFKB2 bind to REL, RELA, or RELB to form the NFKB complex. The NFKB1/RELA heterodimer is the most abundant form of NFKB. The NFKB complex is inactivated by I-kappa-B proteins that keep it trapped in the cytoplasm. Phosphorylation of serine residues on the I-kappa B proteins mark them for ubiquitination and destruction, and NFKB translocates to the nucleus where it binds DNA. Transforming protein Tax inhibits p53 transcriptional activity through the NFKB signaling pathway, specifically via the p65 (RelA) subunit. The inhibition of p53 activity is dependent upon phosphorylation of p65 (RelA) at ser536 by the upstream kinase IKKB.

Featured V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody
LS-B653 is a rabbit polyclonal antibody that LifeSpan has tested extensively in immunohistochemistry (IHC) and is an excellent antibody for use in formalin-fixed paraffin embedded tissues. Multiple tissues were immunolabeled and the results were interpreted by a LifeSpan pathologist. This image shows an example of staining in formalin-fixed paraffin embedded tissue.
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V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibodies (91)

Target	Catalog	Type	Form	Epitope	Assay	Reactivity	Size	Price
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B653	Rabbit		C-Terminus	IHC-P, WB, IP, IF, GS, ELISA	Human	50 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B53	Rabbit			IHC-P, WB, ELISA	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B1488	Rabbit IgG		Ser536	IHC-P, WB	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B652	Rabbit		pSer529	IHC-P, WB, IP, ELISA	Human, Mouse, Rat	50 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B654	Rabbit		pSer276	IHC-P, WB, IP, ELISA	Human, Mouse, Rat	50 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C537	Mouse IgG1		aa526-539	WB, Flo	Human, Mouse	100 µg	$280
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C708	Rabbit IgG		aa538-546	WB	Human, Mouse	200 µl	$270
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9296	Rabbit IgG		N-Terminus	IHC, WB, IF, ELISA	Human	100 µg	$480
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C53845	Rabbit		pSer529	WB	Human, Mouse	50 µl	$456
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C49525	Rabbit IgG		C-Terminus	IHC-P, ICC, WB, IP, Flo	Human	100 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C88697	Rabbit IgG	Azide-free		IHC-P, WB	Human, Bovine, Dog, Xenopus, Hamster, Mouse, Porcine, Rabbit, Rat	500 µg	$465
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C88763	Rabbit IgG			IHC-P, WB	Human, Rabbit, Rat	20 µg	$260
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C88696	Rabbit IgG			IHC-P, WB	Human, Bovine, Dog, Xenopus, Hamster, Mouse, Porcine, Rabbit, Rat	100 µg	$260
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C33806	Rabbit		Internal	IHC, WB	Human, Rabbit, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C50564	Rabbit		Internal	IHC, WB	Human, Rabbit, Rat	50 µg	$365
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9284	Mouse IgG3			IHC-P, IHC-Fr, ICC, WB, Flo, IF, GS, ELISA	Human	100 µg	$545
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37637	Rabbit		C-Terminus	IHC-P, IHC-Fr	Human	500 µl	$490
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C85939	Rabbit			IHC, WB, IP, ELISA		100 µl	$485
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C18905	Rabbit		N-Terminus	IHC, WB, IF, ELISA	Human	100 µg	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51709	Rabbit		C-Terminus	IHC, WB, IP	Human	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C96914	Rabbit		pSer536	IHC-P, WB, ELISA	Human	100 µg	$267
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C96915	Rabbit		pSer536	IHC-P, WB, ELISA	Human	100 µg	$267
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C48125	Mouse IgG1			IHC, WB, IP	Human, Mouse, Rat	100 µg	$435
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C42658	Rabbit IgG		pSer536	IHC-P, WB, ELISA	Human	50 µg	$335
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47752	Rabbit		Ser276	IHC, WB, ELISA	Human, Bovine, Mouse, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47775	Rabbit		Internal	IHC, WB, IP	Human, Bovine, Mouse, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51218	Rabbit IgG		pSer529	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51113	Rabbit IgG		pSer536	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51110	Rabbit IgG		pThr435	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51426	Rabbit IgG		pSer311	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51425	Rabbit IgG		Ser311	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51345	Rabbit IgG		Ser529	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51109	Rabbit IgG		pSer276	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C48148	Rabbit			IHC, WB	Mouse, Human, Rat	100 µg	$355
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C34249	Rabbit IgG		Ser276	IHC, WB	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C34009	Rabbit IgG		pSer468	IHC, WB	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51108	Rabbit IgG		Ser468	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51103	Rabbit IgG		Thr435	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51102	Rabbit IgG		Ser276	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51464	Rabbit IgG		Thr254	IHC	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51353	Rabbit IgG		pThr254	IHC	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9299	Rabbit IgG		C-Terminus	IHC-Fr, WB, IP, GS, ELISA	Human, Mouse	100 µl	$560
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9291	Rabbit IgG		C-Terminus	IHC, WB, IP, GS, ELISA	Human	100 µl	$435
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37636	Rabbit IgG			IHC, ICC, WB, Flo	Human, Mouse, Rat	100 µl	$445
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9285	Rabbit		C-Terminus	IHC, WB, IP, ELISA	Human, Mouse, Rat	100 µg	$470
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9279	Rabbit IgG			IHC, WB, IP, ELISA	Human, Mouse, Rat	100 µl	$565
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91090	Rabbit		Ser869	IHC, WB	Human	100 µg	$425
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91089	Rabbit		Thr435	IHC, WB	Human	100 µg	$425
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73479	Rabbit IgG		pSer254	IHC, ELISA	Human	40 µg	$320
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91091	Rabbit IgG		Thr505	IHC	Human, Mouse, Rat	40 µg	$305
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91085	Rabbit IgG		pThr505	IHC	Human, Mouse, Rat	40 µg	$320
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C50161	Rabbit IgG		pSer486	ICC, WB, Flo	Human	100 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C18904	Rabbit		C-Terminus	WB, IP, ELISA	Human	100 µl	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C108848	Mouse IgG1			WB, ELISA	Human, Mouse	100 µl	$320
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C50154	Rabbit IgG		pSer536	WB, IP	Human	100 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47311	Rabbit IgG		aa1-50	WB	Human, Chimpanzee, Dog, Monkey, Mouse	100 µg	$375
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47375	Rabbit			WB	Human, Bovine, Chimpanzee, Gorilla, Horse, Monkey, Mouse	100 µg	$270
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C31758	Rabbit IgG			WB	Human	100 µg	$335
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C41295	Rabbit IgG		C-Terminus	WB	Mouse, Human, Rat	50 µl	$180
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C42712	Rabbit IgG		C-Terminus	WB, IP, GS, ELISA	Human, Mouse	0.1 ml	$430
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C42688	Sheep IgG		aa12-317	WB, IP, GS, ELISA	Human	100 µg	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C18903	Rabbit		N-Terminus	WB, IP, ELISA	Human	100 µl	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C86186	Rabbit		C-Terminus	IP, ELISA	Human	100 µl	$625
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C86185	Rabbit		N-Terminus	IP, ELISA	Human	100 µl	$625
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C33933	Rabbit		pSer276	WB, ELISA	Human, Bovine, Mouse, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C63201	Rabbit			WB	Human, Bovine, Canine, Guinea pig, Monkey, Mouse, Porcine, Pig, Rabbit, Rat	100 µl	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C62225	Rabbit IgG			WB	Human, Rat	100 µl	$299
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51112	Rabbit IgG		pSer468	WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C95957	Rabbit		Internal		Human, Rabbit, Rat	0.5 ml	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73488	Sheep IgG			WB, IP, GS, ELISA	Human	50 µg	$540
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73489	Rabbit IgG		N-Terminus	WB, IP, GS, ELISA	Human	100 µl	$535
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9283	Rabbit IgG		C-Terminus	WB, IP, GS, ELISA	Human	100 µl	$330
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9290	Sheep IgG		aa12-317	WB, IP, GS, ELISA	Human	100 µl	$475
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37638	Mouse IgG2a		C-Terminus	WB, GS, ELISA	Human	100 µg	$445
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9289	Rabbit IgG		N-Terminus	WB, IP, ELISA	Human, Mouse	100 µl	$470
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9287	Rabbit IgG		pSer276	WB, IP, ELISA	Human, Mouse, Rat	100 µl	$405
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73493	Mouse IgG1		C-Terminus	ICC, WB	Mouse, Human	100 µl	$540
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73485	Mouse IgG1,k		aa526-539	WB, Flo	Human, Mouse	100 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91086	Rabbit		aa539-551	WB, ELISA	Human	1000 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C75355	Mouse IgG1			ICC, WB	Human, Rat	50 µg	$430
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9298	Rabbit		pSer529	WB, ELISA	Human	100 µl	$480
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9286	Rabbit IgG		pSer536	WB, ELISA	Human, Mouse, Rat	100 µl	$440
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9280	Rabbit IgG		C-Terminus	WB, IP	Human, Mouse, Rat	200 µg	$525
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9297	Rabbit		pSer276	WB, ELISA	Human	100 µl	$480
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9295	Mouse IgG1		aa526-539	WB, Flo	Human, Mouse	100 µg	$465
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73484	Rabbit IgG		aa538-546	WB	Human, Mouse	200 µl	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73486	Rabbit IgG			WB	Human	100 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73492	Mouse IgG1,k	Biotin	aa526-539	WB	Human, Mouse	100 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9288	Rabbit		pSer529	WB	Human, Mouse	100 µl	$500
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9294	Mouse IgG1,k	Biotin	aa526-539	WB	Human, Mouse	100 µg	$485
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37639	Rabbit IgG	AF488	pSer536	Flo	Human	500 µl	$505

V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Target Details

Gene Name:

V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA)

Synonyms:

RELA, nfkb3, nuclear factor kappa-b, subunit 3, transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog a

Target Sequences:

NM_021975 NP_068810.2 Q04206

Features:

Feature Type	Location	Details
Function	1 - 551	NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF- kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52 and the heterodimeric p65-p50 complex appears to be most abundant one. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively. NF-kappa-B is controlled by various mechanisms of post-translational modification and subcellular compartmentalization as well as by
Modification	122 - 122	N6-acetyllysine; by PCAF and EP300
Modification	123 - 123	N6-acetyllysine; by PCAF and EP300
Modification	254 - 254	Phosphothreonine
Modification	276 - 276	Phosphoserine; by RPS6KA4 and RPS6KA5
Modification	281 - 281	Phosphoserine (Probable)
Modification	310 - 310	N6-acetyllysine
Modification	311 - 311	Phosphoserine; by PKC/PRKCZ (By similarity).
Modification	435 - 435	Phosphothreonine
Modification	468 - 468	Phosphoserine; by IKKB and IKKE
Modification	505 - 505	Phosphothreonine; by CHK1
Modification	529 - 529	Phosphoserine; by CK2
Modification	536 - 536	Phosphoserine; by IKKB
Molecular Weight	1 - 551	60219
Similarity	1 - 551	Contains 1 RHD (Rel-like) domain.
Subcellular Location	1 - 551	Nucleus. Cytoplasm. Note=Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B).
Subunit	1 - 551	Component of the NF-kappa-B p65-p50 complex. Component of the NF-kappa-B p65-c-Rel complex. Homodimer; component of the NF- kappa-B p65-p65 complex. Component of the NF-kappa-B p65-p52 complex. May interact with ETHE1. Binds AES and TLE1. Interacts with TP53BP2. Binds to and is phosphorylated by the activated form of either RPS6KA4 or RPS6KA5. Interacts with ING4 and this interaction may be indirect. Interacts with CARM1, USP48 and UNC5CL. Interacts with IRAK1BP1 (By similarity).Interacts with NFKBID (By similarity). Interacts with NFKBIA. Interacts with GSK3B. Interacts with NFKBIB (By similarity). Interacts with NFKBIE. Interacts with NFKBIZ (By similarity). Part of a 70-90 kDa complex at least consisting of CHUK, IKBKB, NFKBIA, RELA, IKBKAP and MAP3K14. Interacts with HDAC3; HDAC3 mediates the deacetylation of RELA. Interacts with HDAC1; the interaction requires non-phosphor

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For Research Use Only. Not intended for human, diagnostic or therapeutic purposes.

The data on this page have been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).