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RELA Antibody
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Rabbit anti-Human Polyclonal Antibody - LS-B53 - LifeSpan BioSciences

Antibody Catalog ID:

LS-B53

Antibody Validation:

This antibody replaces catalog number LS-C18907. It has been validated for use in the following assays: IF.

Antibody Target:

V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA)

Synonyms:

RELA, nfkb3, nuclear factor kappa-b, subunit 3, transcription factor p65, v-rel avian reticuloendotheliosis viral oncogene homolog a

Host:

RELA antibody was produced in Rabbit

Antigen Species:

RELA antibody was raised against Human

Clonality:

Polyclonal

Antigen Type:

Synthetic peptide - KLH conjugated

Immunogen:

RELA antibody was raised against synthetic peptide

Antibody Specificity:

Residues surrounding S536 of human p65 (RelA) protein.

Predicted Species Reactivity:

Mouse, Rat

Purification:

Immunoaffinity Chromatography

Presentation:

0.02 M potassium phosphate, 0.15 M sodium chloride, pH 7.2, 0.01% sodium azide.

Recommended Storage:

+4°C or -20°C, Avoid repeated freezing and thawing.

Antibody Usage Summary:

Immunohistochemistry: LS-B53 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D1, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B53 was determined to be 5 ug/ml.

Antibody Uses:

Immunohistochemistry - Paraffin (IHC-P) (5 µg/ml ), Western blot (WB) (1:200 - 1:2000 ), ELISA (1:1000 - 1:6000 ) (Optimal dilution to be determined by the researcher)

Size:

50 µg

Concentration:

1 mg/ml

Antibody Price (USD):

$350

Immunohistochemistry Image:

Kidney: Formalin-Fixed Paraffin-Embedded (FFPE)

Recommended Secondary Antibodies (1)

Target	Catalog	Type	Form	Epitope	Assay	Reactivity	Size	Price	Buy
Rabbit IgG Antibody	LS-D1	Goat	Biotin			Rabbit	750 µg	$100

Related V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibodies (90)

Target	Catalog	Type	Form	Epitope	Assay	Reactivity	Size	Price
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B653	Rabbit		C-Terminus	WB, IP, ELISA, IF, IHC-P, GS	Human	50 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B1488	Rabbit IgG		Ser536	WB, IHC-P	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B652	Rabbit		pSer529	WB, IP, ELISA, IHC-P	Human, Mouse, Rat	50 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-B654	Rabbit		pSer276	WB, IP, ELISA, IHC-P	Human, Mouse, Rat	50 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C537	Mouse IgG1		aa526-539	WB, Flo	Human, Mouse	100 µg	$280
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C708	Rabbit IgG		aa538-546	WB	Human, Mouse	200 µl	$270
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9296	Rabbit IgG		N-Terminus	IHC, WB, ELISA, IF	Human	100 µg	$480
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C53845	Rabbit		pSer529	WB	Human, Mouse	50 µl	$456
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C49525	Rabbit IgG		C-Terminus	ICC, WB, IP, Flo, IHC-P	Human	100 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C33806	Rabbit		Internal	IHC, WB	Human, Rabbit, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C50564	Rabbit		Internal	IHC, WB	Human, Rabbit, Rat	50 µg	$365
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C88696	Rabbit IgG			WB, IHC-P	Human, Bovine, Dog, Xenopus, Hamster, Mouse, Porcine, Rabbit, Rat	100 µg	$260
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C88697	Rabbit IgG	Azide-free		WB, IHC-P	Human, Bovine, Dog, Xenopus, Hamster, Mouse, Porcine, Rabbit, Rat	500 µg	$465
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C88763	Rabbit IgG			WB, IHC-P	Human, Rabbit, Rat	20 µg	$260
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9284	Mouse IgG3			ICC, WB, Flo, ELISA, IF, IHC-P, IHC-Fr, GS	Human	100 µg	$545
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37637	Rabbit		C-Terminus	IHC-P, IHC-Fr	Human	500 µl	$490
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C18905	Rabbit		N-Terminus	IHC, WB, ELISA, IF	Human	100 µg	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C85939	Rabbit			IHC, WB, IP, ELISA		100 µl	$485
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C42658	Rabbit IgG		pSer536	WB, ELISA, IHC-P	Human	50 µg	$335
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47752	Rabbit		Ser276	IHC, WB, ELISA	Human, Bovine, Mouse, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47775	Rabbit		Internal	IHC, WB, IP	Human, Bovine, Mouse, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C48125	Mouse IgG1			IHC, WB, IP	Human, Mouse, Rat	100 µg	$435
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51709	Rabbit		C-Terminus	IHC, WB, IP	Human	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C96914	Rabbit		pSer536	WB, ELISA, IHC-P	Human	100 µg	$267
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C96915	Rabbit		pSer536	WB, ELISA, IHC-P	Human	100 µg	$267
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C34009	Rabbit IgG		pSer468	IHC, WB	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C34249	Rabbit IgG		Ser276	IHC, WB	Human, Mouse, Rat	50 µg	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C48148	Rabbit			IHC, WB	Mouse, Human, Rat	100 µg	$355
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51102	Rabbit IgG		Ser276	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51103	Rabbit IgG		Thr435	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51108	Rabbit IgG		Ser468	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51109	Rabbit IgG		pSer276	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51110	Rabbit IgG		pThr435	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51113	Rabbit IgG		pSer536	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51218	Rabbit IgG		pSer529	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51345	Rabbit IgG		Ser529	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51425	Rabbit IgG		Ser311	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51426	Rabbit IgG		pSer311	IHC, WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51353	Rabbit IgG		pThr254	IHC	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51464	Rabbit IgG		Thr254	IHC	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9291	Rabbit IgG		C-Terminus	IHC, WB, IP, ELISA, GS	Human	100 µl	$435
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9299	Rabbit IgG		C-Terminus	WB, IP, ELISA, IHC-Fr, GS	Human, Mouse	100 µl	$560
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9279	Rabbit IgG			IHC, WB, IP, ELISA	Human, Mouse, Rat	100 µl	$565
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9285	Rabbit		C-Terminus	IHC, WB, IP, ELISA	Human, Mouse, Rat	100 µg	$470
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37636	Rabbit IgG			ICC, IHC, WB, Flo	Human, Mouse, Rat	100 µl	$445
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73479	Rabbit IgG		pSer254	IHC, ELISA	Human	40 µg	$320
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91089	Rabbit		Thr435	IHC, WB	Human	100 µg	$425
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91090	Rabbit		Ser869	IHC, WB	Human	100 µg	$425
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91085	Rabbit IgG		pThr505	IHC	Human, Mouse, Rat	40 µg	$320
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91091	Rabbit IgG		Thr505	IHC	Human, Mouse, Rat	40 µg	$305
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C18904	Rabbit		C-Terminus	WB, IP, ELISA	Human	100 µl	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C50161	Rabbit IgG		pSer486	ICC, WB, Flo	Human	100 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C50154	Rabbit IgG		pSer536	WB, IP	Human	100 µl	$350
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C108848	Mouse IgG1			WB, ELISA	Human, Mouse	100 µl	$320
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C31758	Rabbit IgG			WB	Human	100 µg	$335
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C41295	Rabbit IgG		C-Terminus	WB	Mouse, Human, Rat	50 µl	$180
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47311	Rabbit IgG		aa1-50	WB	Human, Chimpanzee, Dog, Monkey, Mouse	100 µg	$375
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C47375	Rabbit			WB	Human, Bovine, Chimpanzee, Gorilla, Horse, Monkey, Mouse	100 µg	$270
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C42688	Sheep IgG		aa12-317	WB, IP, ELISA, GS	Human	100 µg	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C42712	Rabbit IgG		C-Terminus	WB, IP, ELISA, GS	Human, Mouse	0.1 ml	$430
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C18903	Rabbit		N-Terminus	WB, IP, ELISA	Human	100 µl	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C33933	Rabbit		pSer276	WB, ELISA	Human, Bovine, Mouse, Rat	50 µg	$295
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C86185	Rabbit		N-Terminus	IP, ELISA	Human	100 µl	$625
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C86186	Rabbit		C-Terminus	IP, ELISA	Human	100 µl	$625
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C51112	Rabbit IgG		pSer468	WB	Human, Mouse, Rat	40 µg	$245
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C62225	Rabbit IgG			WB	Human, Rat	100 µl	$299
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C63201	Rabbit			WB	Human, Bovine, Canine, Guinea pig, Monkey, Mouse, Porcine, Pig, Rabbit, Rat	100 µl	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C95957	Rabbit		Internal		Human, Rabbit, Rat	0.5 ml	$345
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9283	Rabbit IgG		C-Terminus	WB, IP, ELISA, GS	Human	100 µl	$330
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9290	Sheep IgG		aa12-317	WB, IP, ELISA, GS	Human	100 µl	$475
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73488	Sheep IgG			WB, IP, ELISA, GS	Human	50 µg	$540
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73489	Rabbit IgG		N-Terminus	WB, IP, ELISA, GS	Human	100 µl	$535
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9287	Rabbit IgG		pSer276	WB, IP, ELISA	Human, Mouse, Rat	100 µl	$405
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9289	Rabbit IgG		N-Terminus	WB, IP, ELISA	Human, Mouse	100 µl	$470
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37638	Mouse IgG2a		C-Terminus	WB, ELISA, GS	Human	100 µg	$445
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9280	Rabbit IgG		C-Terminus	WB, IP	Human, Mouse, Rat	200 µg	$525
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9286	Rabbit IgG		pSer536	WB, ELISA	Human, Mouse, Rat	100 µl	$440
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9295	Mouse IgG1		aa526-539	WB, Flo	Human, Mouse	100 µg	$465
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9297	Rabbit		pSer276	WB, ELISA	Human	100 µl	$480
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9298	Rabbit		pSer529	WB, ELISA	Human	100 µl	$480
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73485	Mouse IgG1,k		aa526-539	WB, Flo	Human, Mouse	100 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73493	Mouse IgG1		C-Terminus	ICC, WB	Mouse, Human	100 µl	$540
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C75355	Mouse IgG1			ICC, WB	Human, Rat	50 µg	$430
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C91086	Rabbit		aa539-551	WB, ELISA	Human	1000 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9288	Rabbit		pSer529	WB	Human, Mouse	100 µl	$500
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C9294	Mouse IgG1,k	Biotin	aa526-539	WB	Human, Mouse	100 µg	$485
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C37639	Rabbit IgG	AF488	pSer536	Flo	Human	500 µl	$505
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73484	Rabbit IgG		aa538-546	WB	Human, Mouse	200 µl	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73486	Rabbit IgG			WB	Human	100 µg	$510
V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Antibody	LS-C73492	Mouse IgG1,k	Biotin	aa526-539	WB	Human, Mouse	100 µg	$510

Antibody Summary:
NFkB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFkB bound to IkB. NFkB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFKB1) subunits. Other identified subunits include p52 (NFKB2), cRel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFkB subunit p65, similar to p50/p65 heterodimers. Low levels of p52 and p50 homodimers can also exist in cells. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by IkB-a. IkB-a binds to the p65 subunit, preventing nuclear localization, and DNA binding. Activators mediate a rapid phosphorylation of IkB by IkB kinase (IKK), which results in subsequent ubiquitination and proteolytic degradation. NFkB is then transported to the nucleus, where it activates transcription of target genes through binding to NFkB target sequences within the promoter. The HTLV-I protein Tax can induce constitutive NFkB activation through phosphorylation of both I?B-a and I?B-. The transforming protein Tax inhibits p53 transcriptional activity through the NFkB signaling pathway, specifically via the p65 (RelA) subunit. The inhibition of p53 activity is dependent upon phosphorylation of p65 (RelA) at S536 by the upstream kinase IKK.

Requested From:

United States

For Research Use Only. Not intended for human, diagnostic or therapeutic purposes.

The data on this page have been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

V-rel Reticuloendotheliosis Viral Oncogene Homolog A (RELA) Rabbit anti-Human Polyclonal Antibody - LS-B53 - LifeSpan BioSciences