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TNFRSF6B / DCR3

tumor necrosis factor receptor superfamily, member 6b, decoy

Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors. Several novel members in the TNFR family including DR3, DR4, DR5, and DR6 were recently discovered and function as cell death receptors. Two decoy receptors, DcR1 and DcR2, were recently identified to compete with DR4 and DR5 for their ligand TRAIL binding. A novel decoy receptor was more recently discovered and designated DcR3 and TR6, respectively. Unlike DcR1 and DcR2, DcR3 is a soluble rather than a membrane associated molecule. DcR3 binds to FasL and LIGHT and inhibits FasL and LIGHT induced apoptosis. DcR3 transcript is expressed in a number of lung and colon carcinomas and in some normal tissues.

Gene Name: tumor necrosis factor receptor superfamily, member 6b, decoy
Family/Subfamily: TNF Receptor , not assigned-TNF Receptor
Synonyms: TNFRSF6B, Decoy receptor 3, DJ583P15.1.1, DCR3, M68E, M68, TR6, Decoy receptor for Fas ligand
Target Sequences: NM_032945 NP_003814.1 O95407

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Products
Antibodies (30)
Primary (30)
TNFRSF6B / DCR3 (30)
Human (30)
Mouse (10)
Rat (7)
IHC (23)
IHC-P (8)
WB (25)
Flo (8)
ELISA (14)
ICC (2)
IF (7)
IP (1)
Peptide-ELISA (3)
rabbit (27)
mouse (3)
Product Group
IHCPlus (1)
IgG (23)
IgG1 (2)
IgG2a,k (1)
monoclonal mc (3)
polyclonal pc (27)
3C5H10 (1)
7G5 (1)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (2)
Preservative Free (1)
Unconjugated (20)
aa22-48 (7)
N-Terminus (2)
220-300 aa, C-terminal (1)
C-Terminus (1)
Gly287 (1)
aa238-287 (1)
aa24-300 (1)
aa251-300 (1)
No (30)
TNFRSF6B / DCR3 Antibody - Immunoperoxidase of monoclonal antibody to TNFRSF6B on formalin-fixed paraffin-embedded human tonsil. [antibody concentration 3 ug/ml]
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TNFRSF6B / DCR3 Mouse anti-Human Monoclonal (7G5) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100 µg/$423
TNFRSF6B / DCR3 Antibody - Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using TNFRSF6B Antibody. The picture on the right is blocked with the synthesized peptide.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
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TNFRSF6B / DCR3 Mouse anti-Human Monoclonal (aa24-300) (Biotin) Antibody
Human
ELISA
Biotin Conjugated
250 µg/$1,068
TNFRSF6B / DCR3 Antibody - TNFRSF6B antibody immunohistochemistry of formalin-fixed and paraffin-embedded human colon carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TNFRSF6B / DCR3 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µg/$729
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (HRP) Antibody
Mouse, Rat, Human
IHC, WB
HRP Conjugated
100 µl/$913
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (PE) Antibody
Mouse, Rat, Human
IHC, WB
PE Conjugated
100 µl/$913
TNFRSF6B / DCR3 Antibody - Immunohistochemistry of human heart with Rabbit anti-Human DcR3
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
0.1 mg/$470
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$688
TNFRSF6B / DCR3 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using TNFRSF6B antibody.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
TNFRSF6B / DCR3 Antibody - 1:100 staining human brain tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TNFRSF6B / DCR3 Antibody - Western blot of HepG2 cell lysate using TNFRSF6B Antibody
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
TNFRSF6B / DCR3 Antibody - Western blot of DcR3 antibody
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (220-300 aa, C-terminal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) (FITC) Antibody
Human
ELISA, Flo, IHC, WB
FITC Conjugated
200 µl/$952
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) (Azide-free) (HRP) Antibody
Human
ELISA, Flo, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa22-48) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
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TNFRSF6B / DCR3 Mouse anti-Human Monoclonal (3C5H10) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
TNFRSF6B / DCR3 Antibody - IHC of DcR3 (G287) pAb in paraffin-embedded human colon carcinoma tissue.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (Gly287) Antibody
Human
IF, IHC, IHC-P
Unconjugated
50 µl/$321; 100 µl/$403
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IHC-P
Unconjugated, Preservative Free
50 µl/$317; 100 µl/$375; 200 µl/$473
TNFRSF6B / DCR3 Antibody - Immunohistochemistry of DcR1 in human heart tissue with DcR1 antibody at 1 µg/ml.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
TNFRSF6B / DCR3 Antibody - Western blot analysis of the lysates from HT-29 cells using TNFRSF6B antibody.
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TNFRSF6B / DCR3 Rabbit anti-Human Polyclonal (aa238-287) Antibody
Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).