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SLC22A5 / OCTN2

solute carrier family 22 (organic cation/carnitine transporter), member 5

Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: solute carrier family 22 (organic cation/carnitine transporter), member 5
Family/Subfamily: Transporter , Organic cation transporter
Synonyms: SLC22A5, CDSP, OCTN2VT, OCTN2, UST2
Target Sequences: NM_003060 NP_003051.1 O76082

Publications (1)

1
Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Kim HI, Raffler J, Lu W, Lee JJ, Abbey D, Saleheen D, Rabinowitz JD, Bennett MJ, Hand NJ, Brown C, Rader DJ. American journal of human genetics. 2017 October;101:489-502. (Mouse) [Full Text Article] [PubMed:28942964] [PMC:PMC5630162] Related Antibodies: LS-C313281.

☰ Filters
Antibodies (26)
Proteins (4)
Over-Expression Lysate (2)
Primary (26)
Recombinant (2)
SLC22A5 / OCTN2 (30)
Human (24)
Mouse (9)
Rat (11)
Bovine (3)
Chimpanzee (3)
Dog (3)
Gibbon (6)
Horse (3)
Monkey (3)
Orangutan (3)
Pig (3)
IHC (6)
IHC-P (2)
WB (22)
ELISA (9)
ICC (1)
IF (3)
Peptide-ELISA (2)
rabbit (26)
Product Group
IHCPlus (2)
IgG (14)
polyclonal pc (26)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
Unconjugated (17)
C-Terminus (6)
aa305-354 (4)
270-350 aa, Internal (1)
aa282-331 (1)
aa531-547 (1)
No (29)
Yes (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (1)
Select
SLC22A5 / OCTN2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µl/$801
SLC22A5 / OCTN2 Antibody - WB of SLC22A5 / OCTN2 antibody. Lane 1: Rat Kidney Tissue Lysate. Lane 2: Rat Skeletal Muscles Tissue Lysate. Lane 3: Mouse Liver Tissue Lysate. Lane 4: HEPA Cell Lysate. Lane 5: NIH3T3 Cell Lysate.
Select
SLC22A5 / OCTN2 Rabbit anti-Mouse Polyclonal (aa531-547) Antibody
Mouse, Rat
WB
Unconjugated
10 µg/$318; 100 µg/$470
SLC22A5 / OCTN2 Antibody
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µl/$286; 100 µl/$321
SLC22A5 / OCTN2 Antibody - Anti-SLC22A5 / OCTN2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:50.
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SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (aa282-331) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Select
SLC22A5 / OCTN2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
SLC22A5 / OCTN2 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
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SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$460
SLC22A5 / OCTN2 Antibody - Immunofluorescence staining of Hela cells diluted at 1:33, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C.The Secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA
FITC Conjugated
50 µg/$294; 100 µg/$360
SLC22A5 / OCTN2 Antibody - SLC22A5 antibody Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (aa305-354) Antibody
Human
WB
Unconjugated
100 µl/$424
SLC22A5 / OCTN2 Antibody - SLC22A5 antibody Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (aa305-354) (HRP) Antibody
Dog, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
SLC22A5 / OCTN2 Antibody - SLC22A5 antibody Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (aa305-354) (Biotin) Antibody
Dog, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
SLC22A5 / OCTN2 Antibody - SLC22A5 antibody Western blot of 3 Cell lysate. Antibody concentration 1 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (aa305-354) (FITC) Antibody
Dog, Bovine, Rat, Pig, Horse, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
SLC22A5 / OCTN2 Antibody - Western blot of extracts of MCF-7 cell lines, using SLC22A5 antibody.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (270-350 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
SLC22A5 / OCTN2 Antibody - Western blot analysis of extracts of rat Heart cells using SLC22A5 antibody. The lane on the left is treated with the antigen-specific peptide.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SLC22A5 / OCTN2 Antibody - Immunohistochemistry of paraffin-embedded Rat brain using SLC22A5 Polyclonal Antibody at dilution of 1:100 (40x lens).
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
SLC22A5 / OCTN2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
SLC22A5 / OCTN2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody
Human, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
SLC22A5 / OCTN2 Antibody -  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody
Human, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
SLC22A5 / OCTN2 Antibody - Western blot analysis of OCTN2 expression in mouse kidney (A), rat kidney (B), HEK293T (C), K562 (D), Hela (E) whole cell lysates.
Select
SLC22A5 / OCTN2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Viewing 1-25 of 30 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).