OTX2

orthodenticle homeobox 2

OTX2 is a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

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Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

OTX2 (7)

Publications

No (7)

Tag

His (1)

His, N-Terminal (1)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

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Human OTX2 Protein (Recombinant His-SUMO) (aa1-297) - LS-G21030

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

48.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human OTX2 Protein (Recombinant His, N-Terminal) - LS-G143990

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

31.6 kDa

Price:

50 µg/$419

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OTX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G105443

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.5 kDa

Price:

100 µg/$494

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OTX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110633

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

100 µg/$494

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Human OTX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76604

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.2 kDa

Price:

20 µg/$150

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Human OTX2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76605

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

31.5 kDa

Price:

20 µg/$150

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Human OTX2 Protein (Recombinant His) (aa37-116) - LS-G140839

Source:

E. coli

Sequence Length:

79 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

8.8 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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