OTX2

orthodenticle homeobox 2

OTX2 is a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.

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Products

Antibodies (45)

Proteins (7)

ELISA Kits (4)

Type

Custom (2)

Over-Expression Lysate (4)

Primary (45)

Recombinant (3)

Sandwich (2)

Target

OTX2 (56)

Reactivity

Human (47)

Mouse (11)

Rat (16)

Bat (10)

Bovine (11)

Chicken (5)

Chimpanzee (10)

Dog (11)

Gibbon (10)

Guinea pig (9)

Hamster (11)

Horse (11)

Monkey (1)

Orangutan (1)

Pig (11)

Rabbit (11)

Sheep (11)

Xenopus (8)

Zebrafish (6)

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Application

IHC (18)

IHC-P (3)

WB (43)

Flo (4)

ELISA (11)

ICC (2)

IF (5)

IP (1)

Peptide-ELISA (1)

Host

rabbit (31)

mouse (14)

Isotype

IgG (20)

IgG1 (11)

IgG1,k (1)

IgG2b (2)

Clonality

monoclonal mc (14)

polyclonal pc (31)

Clone

1313CT817.185.162 (1)

1H12C4B5 (2)

1H12G8B2 (2)

OTI1A1 (2)

OTI1B2 (2)

OTI2B3 (2)

OTI3G9 (2)

Format

96-Well Strip Plate (4)

Biotin Conjugated (4)

Carrier-free (4)

FITC Conjugated (4)

HRP Conjugated (4)

Unconjugated (33)

Epitope

aa108-157 (4)

aa110-159 (4)

aa86-135 (4)

N-Terminus (2)

aa102-135 (1)

aa140-280 (1)

aa201-226 (1)

aa258-289 (1)

aa266-296 (1)

Publications

No (56)

Sample Type

Plasma (3)

Serum (3)

Tissue Homogenates (1)

Tag

His (1)

His, N-Terminal (1)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (5)

Source

293T Cells (2)

E. coli (3)

HEK 293 Cells (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (1)

Select

OTX2 Antibody (clone 1H12C4B5) LS-C169367

Antibody:

OTX2 Mouse anti-Human Monoclonal (1H12C4B5) Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

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OTX2 Antibody (aa140-280) LS-C376252

Antibody:

OTX2 Rabbit anti-Human Polyclonal (aa140-280) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

Select

OTX2 Antibody (clone 1H12G8B2) LS-C169368

Antibody:

OTX2 Mouse anti-Human Monoclonal (1H12G8B2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$459

Select

OTX2 Antibody (clone 1H12C4B5) LS-C758938

Antibody:

OTX2 Mouse anti-Human Monoclonal (1H12C4B5) Antibody

Reactivity:

Human

Applications:

Flo, ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

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OTX2 Antibody LS-C812728

Antibody:

OTX2 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IF, IHC, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

Select

OTX2 Antibody LS-C334079

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

Select

OTX2 Antibody (clone 1H12G8B2) LS-C758941

Antibody:

OTX2 Mouse anti-Human Monoclonal (1H12G8B2) Antibody

Reactivity:

Human

Applications:

ICC, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$541

Select

OTX2 Antibody (aa108-157) LS-C109663

Antibody:

OTX2 Rabbit anti-Human Polyclonal (aa108-157) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

OTX2 Antibody (aa86-135) LS-C29716

Antibody:

OTX2 Rabbit anti-Human Polyclonal (aa86-135) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

OTX2 Antibody (aa266-296) LS-C389076

Antibody:

OTX2 Rabbit anti-Human Polyclonal (aa266-296) Antibody

Reactivity:

Xenopus, Chicken, Sheep, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$575

Select

OTX2 Antibody LS-C667393

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, Flo, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

Select

Human OTX2 Protein (Recombinant His-SUMO) (aa1-297) - LS-G21030

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

48.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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OTX2 Antibody (clone OTI1A1) LS-C794971

Antibody:

OTX2 Mouse anti-Human Monoclonal (OTI1A1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

OTX2 Antibody (clone OTI1A1, Carrier-free) LS-C792101

Antibody:

OTX2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A1) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

OTX2 Antibody (clone OTI2B3) LS-C794972

Antibody:

OTX2 Mouse anti-Human Monoclonal (OTI2B3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$434

Select

OTX2 Antibody (clone OTI2B3, Carrier-free) LS-C799649

Antibody:

OTX2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2B3) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

OTX2 Antibody (N-Terminus) LS-C153466

Antibody:

OTX2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

Select

OTX2 Antibody LS-C806664

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

OTX2 Antibody (N-Terminus) LS-C144921

Antibody:

OTX2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

Select

OTX2 Antibody LS-C318146

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

OTX2 Antibody (HRP) LS-C319028

Antibody:

OTX2 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

OTX2 Antibody (Biotin) LS-C318147

Antibody:

OTX2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin

• Unconjugated
• HRP
• Biotin

Select

OTX2 Antibody LS-C341629

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

Select

OTX2 Antibody LS-C768754

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

OTX2 Antibody LS-C749049

Antibody:

OTX2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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