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MUC5AC

mucin 5AC, oligomeric mucus/gel-forming

MUC5AC has been isolated from airway secretions. It is found in the protective film of mucus coating the mucosal surfaces of the respiratory tract and the normal gastrointestinal tissues. Mucins are also expressed at low levels in human fetal gut. MUC5AC is involved in epithelial cell proliferation and differentiation in adult airway mucosa and can be used as a marker for hypersecretory disorders. MUC5AC has also been observed in various tumors. For instance it is expressed in primary mucinous ovarian tumors but not in colonic carcinoma metastatic to the ovary, which makes it a useful marker to distinguish the two types of cancer.

Gene Name: mucin 5AC, oligomeric mucus/gel-forming
Synonyms: MUC5AC, Gastric mucin, Major airway glycoprotein, Muc5/5ac, Mucin-5AC, LeB, Lewis B blood group antigen, Tracheobronchial mucin, TBM, MUC-5AC, MUC5
Target Sequences: AJ001403 CAA04738.1 P98088

Publications (6)

1
A beneficiary role for neuraminidase in influenza virus penetration through the respiratory mucus. Yang X, Steukers L, Forier K, Xiong R, Braeckmans K, Van Reeth K, Nauwynck H. PloS one. 2014 9:e110026. (IHC-P; Human) [Full Text Article] [PubMed:25333824] [PMC:PMC4198190]
2
Limbal niche cells: a novel feeder cell for autologous cultivated oral mucosal epithelial transplantation. Duan CY, Xie HT, Zhao XY, Zhang MC. Regenerative medicine. 2019 January;14:49-62. [Full Text Article] [PubMed:30572808] Related Antibodies: LS-C390690.
3
Vagal sensory neurons drive mucous cell metaplasia. Sébastien Talbot, Benjamin Doyle, Junwei Huang, Jo-Chiao Wang, Maryam Ahmadi, David P Roberson, Ajay Yekkirala, Simmie L Foster, Liam E Browne, Bruce P Bean, Bruce D Levy, Clifford J Woolf. The Journal of allergy and clinical immunology. 2020 June;145:1693-1696.e4. [Full Text Article] [PubMed:31954778]
4
Reduced allergic lung inflammation and airway responsiveness in mice lacking the cytoskeletal protein gelsolin. Maya Mikami, Gene T Yocum, Nicola M Heller, Charles W Emala. American journal of physiology. Lung cellular and molecular physiology. 2020 September; [Full Text Article] [PubMed:32902333] [PMC:PMC7789977]
5
Analysis of mucosal mucins separated by SDS-urea agarose polyacrylamide composite gel electrophoresis. Samah M A Issa, Benjamin L Schulz, Nicolle H Packer, Niclas G Karlsson. Electrophoresis. 2011 December;32:3554-63. [Full Text Article] [PubMed:22120911] Related Antibodies: LS-B2434.
6
Vegetable glycerin e-cigarette aerosols cause airway inflammation and ion channel dysfunction. Michael D Kim, Samuel Chung, John S Dennis, Makoto Yoshida, Carolina Aguiar, Sheyla P Aller, Eliana S Mendes, Andreas Schmid, Juan Sabater, Nathalie Baumlin, Matthias Salathe. Frontiers in pharmacology. 2022 October;13:1012723. [Full Text Article] [PubMed:36225570] [PMC:PMC9549247]
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ELISA Kits (19)
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MUC5AC (19)
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12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (13)
Antibody Pair and Standard (2)
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Yes (3)
Cell Culture Supernatants (6)
Cell Lysates (8)
Plasma (13)
Serum (12)
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MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$764
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Mouse
13.7 - 10000 pg/ml
Chemiluminescent
Plasma, Tissue Homogenates
1 Plate/$871
MUC5AC ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
13.7 - 10000 pg/ml
Chemiluminescent
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$851
MUC5AC ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
15.63 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
MUC5AC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$691
MUC5AC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
MUC5AC ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
MUC5AC ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Rat
54.87 - 40000 pg/ml
Chemiluminescent
Cell Lysates, Tissue Homogenates
1 Plate/$911
MUC5AC ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
156 - 10000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,182; 1000 Wells/$1,747
MUC5AC ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
MUC5AC ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
MUC5AC ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$799
MUC5AC ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,207; 1000 Wells/$1,787
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).