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HPRT1 / HPRT

hypoxanthine phosphoribosyltransferase 1

Converts guanine to guanosine monophosphate, and hypoxanthine to inosine monophosphate. Transfers the 5-phosphoribosyl group from 5-phosphoribosylpyrophosphate onto the purine. Plays a central role in the generation of purine nucleotides through the purine salvage pathway.

Gene Name: hypoxanthine phosphoribosyltransferase 1
Synonyms: HPRT1, HGPRT, HGPRTase, HPRT
Target Sequences: NM_000194 NP_000185.1 P00492

Publications (1)

1
Methylsulfonylmethane inhibits cortisol-induced stress through p53-mediated SDHA/HPRT1 expression in racehorse skeletal muscle cells: A primary step against exercise stress. Nipin Sp, Dong Young Kang, Do Hoon Kim, Hyo Gun Lee, Yeong-Min Park, Il Ho Kim, Hak Kyo Lee, Byung-Wook Cho, Kyoung-Jin Jang, Young Mok Yang. Experimental and therapeutic medicine. 2020 Jan;19:214-222. [Full Text Article] [PubMed:31853292] [PMC:PMC6909739] Related Antibodies: LS-C81245.

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Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
HPRT1 / HPRT (9)
No (9)
6His, N-terminus (2)
GST (1)
His (2)
His-GST (1)
Myc-DDK (Flag) (3)
Human (8)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
HPRT1 / HPRT Protein
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E. coli
His
100 µg/$342; 500 µg/$641; 20 µg/$254
HPRT1 / HPRT Protein
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E. coli
His
28.5 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HPRT1 / HPRT Protein - Purified recombinant protein HPRT1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
24.4 kDa
20 µg/$1,107
HPRT1 / HPRT Protein - 12.5% SDS-PAGE of human HPRT1 stained with Coomassie Blue
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Wheat Germ Extract
GST
49.72 kDa
10 µg/$479; 25 µg/$670
HPRT1 / HPRT Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
24.4 kDa
100 µg/$494
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293T Cells
Myc-DDK (Flag)
24.4 kDa
20 µg/$150
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.79kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
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E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.8 kDa
10 µg/$344; 50 µg/$584
HPRT1 / HPRT Protein - Recombinant Hypoxanthine Phosphoribosyltransferase 1 By SDS-PAGE
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E. coli
His-GST
56.3 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).