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GPR143

G protein-coupled receptor 143

Receptor for tyrosine, L-DOPA and dopamine. After binding to L-DOPA, stimulates Ca2+ influx into the cytoplasm, increases secretion of the neurotrophic factor SERPINF1 and relocalizes beta arrestin at the plasma membrane; this ligand-dependent signaling occurs through a G(q)-mediated pathway in melanocytic cells. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Plays also a role as an intracellular G protein-coupled receptor involved in melanosome biogenesis, organization and transport.

Gene Name: G protein-coupled receptor 143
Family/Subfamily: GPCR , Orphan-U
Synonyms: GPR143, G-protein coupled receptor 143, G protein-coupled receptor 143, NYS6, OA1, Ocular albinism 1, Ocular albinism type 1 protein
Target Sequences: NM_000273 NP_000264.2 P51810

☰ Filters
Antibodies (13)
Proteins (1)
Primary (13)
Recombinant (1)
GPR143 (14)
Human (13)
Mouse (6)
Rat (3)
IHC (2)
IHC-P (1)
WB (6)
ELISA (4)
IF (3)
Peptide-ELISA (1)
rabbit (13)
Product Group
GPCR Database Antibodies (1)
PathPlus Neuro (1)
IgG (10)
polyclonal pc (13)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
Unconjugated (10)
120-200 aa, Internal (1)
C-Terminus (1)
Cytoplasmic Domain (1)
Internal (1)
aa151-200 (1)
No (14)
GST (1)
Human (1)
Wheat Germ Extract (1)
Purified (1)
GPR143 Antibody - Anti-GPR143 antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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GPR143 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
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GPR143 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Human
IHC, WB
Unconjugated
500 µg/$393
GPR143 Antibody - Immunofluorescence analysis of LOVO cells, using GPR143 Antibody. The picture on the right is blocked with the synthesized peptide.
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GPR143 Rabbit anti-Human Polyclonal (aa151-200) Antibody
Mouse, Human
IF, Peptide-ELISA
Unconjugated
50 µl/$334; 100 µl/$397
GPR143 Antibody - Positive Western Blot detected in Rat brain tissue. All lanes: GPR14 antibody at 3.7 µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44 KDa. Observed band size: 44 KDa
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GPR143 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µg/$294; 100 µg/$360
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GPR143 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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GPR143 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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GPR143 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
GPR143 Antibody - Western blot of GPR143 antibody at 1:500 dilution. Lane 1: A549 whole cell lysate. Lane 2: sp2/0 whole cell lysate. Lane 3: PC12 whole cell lysate.
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GPR143 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
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GPR143 Rabbit anti-Human Polyclonal (120-200 aa, Internal) Antibody
Mouse, Human
ELISA, IF
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
GPR143 Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using GPR143 antibody.
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GPR143 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF
Unconjugated
100 µg/$357
GPR143 Antibody
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GPR143 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$332
GPR143 Antibody - Western blot analysis of extracts of various cell lines, using GPR143 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 15s.
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GPR143 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
GPR143 Antibody - Western blot analysis of GPR143 expression in A549 (A); NS-1 (B); PC12 (C) whole cell lysates.
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GPR143 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µl/$299
GPR143 Protein - 12.5% SDS-PAGE of human GPR143 stained with Coomassie Blue
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Wheat Germ Extract
GST
72.5 kDa
2 µg/$439
Viewing 1-14 of 14 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).