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GJB2 / CX26 / Connexin 26

gap junction protein, beta 2, 26kDa

GJB2 / CX26 / Connexin 26 is a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness.

Gene Name: gap junction protein, beta 2, 26kDa
Family/Subfamily: Ion Channel , Connexin
Synonyms: GJB2, Connexin 26, Connexin-26, DFNB1A, DFNA3, DFNB1, Gap junction protein beta 2, KID, HID, PPK, NSRD1, CX26, DFNA3A
Target Sequences: NM_004004 NP_003995.2 P29033

Publications (3)

1
Mouse middle ear ion homeostasis channels and intercellular junctions. Morris LM, DeGagne JM, Kempton JB, Hausman F, Trune DR. PloS one. 2012 7:e39004. (IHC-P; Mouse) [PubMed:22720014] [PMC:PMC3376096] Related Antibodies: LS-C14526.
2
Assembly of the cochlear gap junction macromolecular complex requires connexin 26. Kamiya K, Yum SW, Kurebayashi N, Muraki M, Ogawa K, Karasawa K, Miwa A, Guo X, Gotoh S, Sugitani Y, Yamanaka H, Ito-Kawashima S, Iizuka T, Sakurai T, Noda T, Minowa O, Ikeda K. The Journal of clinical investigation. 2014 124:1598-607. (WB; Mouse) [Full Text Article] [PubMed:24590285] [PMC:PMC3973107] Related Antibodies: LS-B6429.
3
Mammary gland specific knockdown of the physiological surge in Cx26 during lactation retains normal mammary gland development and function. Stewart MK, Plante I, Bechberger JF, Naus CC, Laird DW. PloS one. 2014 9:e101546. (WB; Rat) [Full Text Article] [PubMed:24988191] [PMC:PMC4079510] Related Antibodies: LS-B5511.

☰ Filters
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ELISA Kits (15)
Sandwich (12)
Sandwich CLIA (3)
GJB2 / CX26 / Connexin 26 (15)
Human (5)
Mouse (3)
Rat (3)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (3)
96-Well Strip Plate (10)
No (15)
Plasma (11)
Serum (11)
Tissue Homogenates (4)
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$798
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
19.531 - 1250 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Microplate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
GJB2 / CX26 / Connexin 26 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
19.531 - 1250 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GJB2 / CX26 / Connexin 26 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GJB2 / CX26 / Connexin 26 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GJB2 / CX26 / Connexin 26 ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
7.813 - 500 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).