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GBA / Glucosidase Beta Acid

glucosidase, beta, acid

GBA / Glucosidase Beta Acid encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants.

Gene Name: glucosidase, beta, acid
Synonyms: GBA, Acid beta-glucosidase, Beta-glucocerebrosidase, GBA1, Glucosidase, beta, acid, GLUC, GCB, Lysosomal glucocerebrosidase, Metaxin, MTXN, Glucosylceramidase
Target Sequences: NM_000157 NP_000148.2 P04062

☰ Filters
Products
Proteins (28)
Over-Expression Lysate (10)
Recombinant (18)
GBA / Glucosidase Beta Acid (28)
No (28)
10His, N-terminus (2)
10His-SUMO, N-terminus + Myc, C-terminus (1)
6His, N-terminus (1)
6His-SUMO, N-terminus (1)
GST (1)
GST, N-terminus (2)
GST, N-terminus + His, C-terminus (1)
His (3)
His-GST (2)
Myc-DDK (Flag) (13)
Human (19)
Mouse (3)
Rat (1)
293T Cells (5)
Baculovirus (1)
E. coli (10)
HEK 293 Cells (8)
Wheat Germ Extract (3)
Yeast (1)
Purified (7)
Low endotoxin level (1)
GBA / Glucosidase Beta Acid Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Yeast
6His, N-terminus
57.5 kDa
100 µg/$570; 20 µg/$395; 1 mg/$1,973
GBA / Glucosidase Beta Acid Protein - Recombinant Glucosidase Beta, Acid By SDS-PAGE
Select
E. coli
His-GST
55.5 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
GBA / Glucosidase Beta Acid Protein - Recombinant Glucosidase Beta, Acid By SDS-PAGE
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E. coli
His
12.3 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
GBA / Glucosidase Beta Acid Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GBA / Glucosidase Beta Acid Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
Select
E. coli
319 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
35.2 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
GBA / Glucosidase Beta Acid Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
None
55.6 kDa
1 mg/$1,443; 100 µg/$503; 20 µg/$406
GBA / Glucosidase Beta Acid Protein - Recombinant Glucosidase Beta, Acid By SDS-PAGE
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E. coli
His
20.1 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
GBA / Glucosidase Beta Acid Protein - Recombinant Glucosidase Beta, Acid By SDS-PAGE
Select
E. coli
His-GST
56.1 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
GBA / Glucosidase Beta Acid Protein
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E. coli
GST, N-terminus + His, C-terminus
83.5 kDa
50 µg/$419
GBA / Glucosidase Beta Acid Protein - 12.5% SDS-PAGE of human GBA stained with Coomassie Blue
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Wheat Germ Extract
GST
84.7 kDa
10 µg/$479; 25 µg/$670
GBA / Glucosidase Beta Acid Protein - Purified recombinant protein GBA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$1,107
GBA / Glucosidase Beta Acid Protein - Purified recombinant protein GBA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$1,107
GBA / Glucosidase Beta Acid Protein - Purified recombinant protein GBA was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$1,107
GBA / Glucosidase Beta Acid Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His-SUMO, N-terminus + Myc, C-terminus
75.6 kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GBA / Glucosidase Beta Acid Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Baculovirus
10His, N-terminus
58.1 kDa
100 µg/$810; 20 µg/$387; 1 mg/$1,678
GBA / Glucosidase Beta Acid Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
GBA / Glucosidase Beta Acid Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
GBA / Glucosidase Beta Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.72 kDa
100 µg/$494
GBA / Glucosidase Beta Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
54.9 kDa
100 µg/$494
GBA / Glucosidase Beta Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.72 kDa
100 µg/$494
GBA / Glucosidase Beta Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.72 kDa
100 µg/$710
GBA / Glucosidase Beta Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
59.72 kDa
100 µg/$494
GBA / Glucosidase Beta Acid Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
59.72 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
59.72 kDa
20 µg/$150
Viewing 1-25 of 28 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).