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FGG / Fibrinogen Gamma

fibrinogen gamma chain

Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Gene Name: fibrinogen gamma chain
Synonyms: FGG, Fibrinogen gamma-b chain, Fibrinogen gamma chain, Fibrinogen, gamma polypeptide
Target Sequences: NM_021870 NP_068656.2 P02679

Publications (2)

1
Compression force sensing regulates integrin aIIbß3adhesive function on diabetic platelets. Ju L, McFadyen JD, Al-Daher S, Alwis I, Chen Y, Tønnesen LL, Maiocchi S, Coulter B, Calkin AC, Felner EI, Cohen N, Yuan Y, Schoenwaelder SM, Cooper ME, Zhu C, Jackson SP. Nature communications. 2018 March;9:1087. (Human) [Full Text Article] [PubMed:29540687] [PMC:PMC5852038] Related Antibodies: LS-C418056.
2
A novel urinary biomarker protein panel to identify children with ureteropelvic junction obstruction - A pilot study. Charan Kumar V Devarakonda, Emily R Shearier, Chaoran Hu, James Grady, Jeremy L Balsbaugh, John H Makari, Fernando A Ferrer, Linda H Shapiro. Journal of pediatric urology. 2020 Aug;;16:466.e1-466.e9. [Full Text Article] [PubMed:32620509] [PMC:PMC7529974]

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ELISA Kits (19)
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FGG / Fibrinogen Gamma (19)
Human (6)
Mouse (3)
Rat (4)
Chicken (1)
Dog (1)
Monkey (1)
Porcine (1)
Rabbit (1)
Product Group
DevKit DuoPlus (2)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (15)
Antibody Pair and Standard (2)
No (18)
Yes (1)
Cell Culture Supernatants (2)
Plasma (13)
Serum (8)
Tissue Homogenates (2)
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Human
6.25 - 400 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$730
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Dog
7.8 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.781 - 50 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FGG / Fibrinogen Gamma ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FGG / Fibrinogen Gamma ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
15.625 - 1000 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FGG / Fibrinogen Gamma ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma
1 Plate/$783
FGG / Fibrinogen Gamma ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
FGG / Fibrinogen Gamma ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
FGG / Fibrinogen Gamma ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.312 - 20 pmol/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
3.125 - 200 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
FGG / Fibrinogen Gamma ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Rat
15.62 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma
500 Wells/$1,356; 1000 Wells/$2,037
FGG / Fibrinogen Gamma ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
12.5 - 800 ng/ml
Colorimetric - 450nm (TMB)
Plasma
500 Wells/$1,276; 1000 Wells/$1,903
FGG / Fibrinogen Gamma ELISA Kit
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Sandwich
96-Well Microplate
Mouse
15.6 - 1000 ng/ml
Colorimetric - 450nm (TMB)
Plasma
1 Plate/$734
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).