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FGF10

fibroblast growth factor 10

FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.

Gene Name: fibroblast growth factor 10
Family/Subfamily: HBGF , not assigned-HBGF
Synonyms: FGF10, Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2
Target Sequences: NM_004465 NP_004456.1 O15520

☰ Filters
Products
Proteins (23)
Over-Expression Lysate (2)
Recombinant (20)
FGF10 (23)
Animal-free (1)
No (23)
6His-SUMO, N-terminus (2)
GST (2)
GST, N-terminus (1)
His (1)
His-GST (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (19)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (18)
HEK 293 Cells (1)
Human (1)
Wheat Germ Extract (2)
Purified (9)
Low endotoxin level (10)
Biologically active (7)
Animal-free (1)
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
17.0 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$278; 1 mg/$1,933
Select
E. coli
None
Biologically active
Less than 0.2 EU/µg protein (determined by LAL method).
19.3 kDa (SDS-PAGE)
50 µg/$364; 10 µg/$273; 1 mg/$1,740
Select
E. coli
None
Less than 0.1 ng/µg protein.
19.3 kDa
5 µg/$329; 25 µg/$412; 1000 µg/$3,417
FGF10 Protein
Select
E. coli
None
Less than 0.1 EU/µg protein (determined by LAL method).
19.3 kDa
100 µg/$677
FGF10 Protein
Select
E. coli
GST
46.7 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FGF10 Protein - 12.5% SDS-PAGE of human FGF10 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
49.8 kDa
2 µg/$439
FGF10 Protein - Eukaryotic Fibroblast Growth Factor 10 By SDS-PAGE
Select
Human
None
20.9kDa
50 µg/$752; 10 µg/$331; 200 µg/$1,365; 100 µg/$1,156; 1 mg/$2,648; 500 µg/$2,144; 5 mg/$5,251; 2 mg/$2,838
FGF10 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
FGF10 Protein
Select
E. coli
None
Biologically active
19.1 kDa
5 µg/$282; 100 µg/$957; 500 µg/$1,747
Select
E. coli
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
19.3 kDa
5 µg/$268; 25 µg/$349
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
5 µg/$281; 25 µg/$369
FGF10 Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
19.5kD
10 µg/$288; 50 µg/$442; 500 µg/$1,377; 1 mg/$1,765
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
19.5 kDa
10 µg/$288; 50 µg/$436
FGF10 Protein - The bioactivity was determined in a NIH/3T3 cell proliferation assay. The ED50 was in the range of 0.05 - 0.5 ng/ml.
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
~19 kDa
25 µg/$466; 100 µg/$1,237; 1 mg/$4,915
FGF10 Protein - MCF-7 cell proliferation induced by human FGF-10 in the presence of 2 µg/mL heparin.
Select
E. coli
None
Biologically active
Less than 0.01 ng/µg (determined by LAL method).
The 170 amino acid recombinant protein has a predicted molecular mass of approximately 19.2 kD. The protein migrates at approximately 25 kD in DTT-reducing and non-reducing conditions by SDS-PAGE. The predicted N-terminal amino acid is Met.
10 µg/$291; 25 µg/$355; 100 µg/$731; 500 µg/$1,723
FGF10 Protein - Recombinant Fibroblast Growth Factor 10 By SDS-PAGE
Select
E. coli
His-GST
47.1 kDa
10 µg/$287; 50 µg/$480; 100 µg/$767; 200 µg/$957; 1 mg/$2,089; 500 µg/$1,617; 5 mg/$3,347; 2 mg/$2,278
FGF10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.44 kDa
100 µg/$494
FGF10 Protein - Recombinant Fibroblast Growth Factor 10 By SDS-PAGE
Select
E. coli
His-T7
23.1 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
FGF10 Protein - Recombinant Fibroblast Growth Factor 10 By SDS-PAGE
Select
E. coli
His-GST
46.6 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
FGF10 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.44 kDa
20 µg/$150
FGF10 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FGF10 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
6His-SUMO, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Viewing 1-23 of 23 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).