CYP27B1

cytochrome P450, family 27, subfamily B, polypeptide 1

CYP27B1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The protein encoded by this gene localizes to the inner mitochondrial membrane where it hydroxylates 25-hydroxyvitamin D3 at the 1alpha position. This reaction synthesizes 1alpha,25-dihydroxyvitamin D3, the active form of vitamin D3, which binds to the vitamin D receptor and regulates calcium metabolism. Thus this enzyme regulates the level of biologically active vitamin D and plays an important role in calcium homeostasis. Mutations in this gene can result in vitamin D-dependent rickets type I.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

CYP27B1 (8)

Publications

No (8)

Tag

6His, N-terminus (1)

GST, N-terminus (1)

His, N-Terminal (1)

His-T7 (3)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (2)

Rat (1)

Source

293T Cells (1)

E. coli (5)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human CYP27B1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80281

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.3 kDa

Price:

20 µg/$215

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Mouse CYP27B1 Protein (Recombinant 6His, N-terminus) (aa1-507) - LS-G64299

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human CYP27B1 Protein (Recombinant His, N-Terminal) - LS-G144713

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

56.3 kDa

Price:

50 µg/$419

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Human CYP27B1 Protein (Recombinant GST, N-terminus) (aa409-508) - LS-G58286

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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CYP27B1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99154

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

56.3 kDa

Price:

100 µg/$710

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Human CYP27B1 Protein (Recombinant His-T7) (aa256-508) - LS-G15321

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.9 kDa

Price:

10 µg/$283; 50 µg/$457; 100 µg/$732; 200 µg/$912; 1 mg/$2,032; 500 µg/$1,567; 5 mg/$3,193; 2 mg/$2,219

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Rat CYP27B1 Protein (Recombinant His-T7) (aa251-500) - LS-G15325

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.5 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Mouse CYP27B1 Protein (Recombinant His-T7) (aa258-504) - LS-G15324

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.0 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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