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CTGF

connective tissue growth factor

Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis.

Gene Name: connective tissue growth factor
Family/Subfamily: Hormone , not assigned-Hormone
Synonyms: CTGF, CCN family member 2, CCN2, IGFBP8, IGF-binding protein 8, NOV2, HCS24, IBP-8, IGFBP-8
Target Sequences: NM_001901 NP_001892.1 P29279

Publications (5)

1
A physiological role for connective tissue growth factor in early wound healing. Alfaro MP, Deskins DL, Wallus M, DasGupta J, Davidson JM, Nanney LB, A Guney M, Gannon M, Young PP. Laboratory investigation; a journal of technical methods and pathology. 2013 93:81-95. (ICC, IHC; Mouse) [PubMed:23212098]
2
The Role of Periostin in Capsule Formation on Silicone Implants. Bae HS, Son HY, Lee JP, Chang H, Park JU. BioMed research international. 2018 April;2018:3167037. (Mouse, Human) [Full Text Article] [PubMed:29854742] [PMC:PMC5944282]
3
c-Rel orchestrates energy-dependent epithelial and macrophage reprogramming in fibrosis. Jack Leslie, Marina García Macia, Saimir Luli, Julie C Worrell, William J Reilly, Hannah L Paish, Amber Knox, Ben S Barksby, Lucy M Gee, Marco Y W Zaki, Amy L Collins, Rachel A Burgoyne, Rainie Cameron, Charlotte Bragg, Xin Xu, Git W Chung, Colin D A Brown, Andrew D Blanchard, Carmel B Nanthakumar, Morten Karsdal, Stuart M Robinson, Derek M Manas, Gourab Sen, Jeremy French, Steven A White, Sandra Murphy, Matthias Trost, Johannes L Zakrzewski, Ulf Klein, Robert F Schwabe, Ingmar Mederacke, Colin. Nature metabolism. 2020 November;2:1350-1367. [Full Text Article] [PubMed:33168981] [PMC:PMC7116435]
4
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article] [PubMed:33913810] [PMC:PMC8143797]
5
Calcineurin (PPP3CB) regulates angiotensin II-dependent vascular remodelling by potentiating EGFR signalling in mice. Alexander Nolze, Conny Köhler, Stefanie Ruhs, Katja Quarch, Nicole Strätz, Michael Gekle, Claudia Grossmann. Acta physiologica (Oxford, England). 2021 November;233:e13715. [Full Text Article] [PubMed:34228904]
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Products
ELISA Kits (40)
Competitive EIA (2)
Development Kit (5)
Sandwich (24)
Sandwich CLIA (9)
CTGF (40)
Human (11)
Mouse (8)
Rat (8)
Chicken (1)
Dog (1)
Monkey (1)
Pig (4)
Porcine (1)
Rabbit (4)
Product Group
DevKit Core (1)
DevKit DuoPlus (4)
1000 Wells (1)
12 x 8-Well Microstrips (3)
96-Well Microplate (5)
96-Well Strip Plate (27)
Antibody Pair and Standard (4)
No (38)
Yes (2)
Cell Culture Supernatants (3)
Cell Lysates (3)
Cell Supernatant (1)
Plasma (37)
Serum (38)
Tissue Homogenates (11)
CTGF ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
CTGF ELISA Kit
Select
Sandwich
96-Well Microplate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CTGF ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CTGF ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Mouse
100 - 2500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.625 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$768
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.469 - 30 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$685
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$782
CTGF ELISA Kit
Select
Competitive EIA
96-Well Strip Plate
Human
0.78 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$929
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$929
CTGF ELISA Kit
Select
Sandwich
12 x 8-Well Microstrips
Human
63 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$479
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$728
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
CTGF ELISA Kit
Select
Development Kit
1000 Wells
Human
32 - 4000 pg/ml
Colorimetric - 405nm (ABTS)
1 Test/$540
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
250 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
CTGF ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Human
8 - 500 pg/ml
Chemiluminescent
Cell Lysates, Plasma, Serum
1 Plate/$649
CTGF ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
CTGF ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Mouse
13.72 - 10000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$990
CTGF ELISA Kit
Select
Sandwich CLIA
96-Well Strip Plate
Rat
5.49 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$1,034
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Pig
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$889
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
7.8 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$818
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
31.25 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
CTGF ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
CTGF ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,089; 1000 Wells/$1,589
CTGF ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
15.625 - 1000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).