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CST3 / Cystatin C

cystatin C

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease. In addition, this protein has been shown to have an antimicrobial function, inhibiting the replication of herpes simplex virus. Alternative splicing results in multiple transcript variants encoding a single protein.

Gene Name: cystatin C
Synonyms: CST3, ARMD11, BA218C14.4 (cystatin C), Cystatin-3, Cystatin 3, Cystatin C, Cystatin-C, Gamma-trace, Post-gamma-globulin
Target Sequences: NM_000099 NP_000090.1 P01034

☰ Filters
Products
Proteins (31)
Native (1)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (26)
CST3 / Cystatin C (31)
No (31)
10His, N-terminus + Myc, C-terminus (1)
6His, C-terminus (2)
6His, N-terminus (5)
8His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (7)
His, N-Terminal (2)
His, N-terminus (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Bovine (1)
Chicken (1)
Dog (1)
Human (21)
Mouse (3)
Pig (1)
Rat (2)
293T Cells (1)
E. coli (15)
HEK 293 Cells (5)
Human (1)
Human Cells (5)
Mammalian Cells (2)
Wheat Germ Extract (2)
Purified (5)
Low endotoxin level (11)
CST3 / Cystatin C Protein - Recombinant Cystatin 3 By SDS-PAGE
Select
E. coli
6His, N-terminus
14.5 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
CST3 / Cystatin C Protein - Recombinant Cystatin 3 (CST3) by SDS-PAGE
Select
E. coli
His, N-Terminal
16kDa
10 µg/$291; 50 µg/$502; 200 µg/$1,002; 100 µg/$802; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
CST3 / Cystatin C Protein - Recombinant Human Cystatin C/CST3 Protein (His Tag)-Elabsicence
Select
E. coli
His, N-terminus
13.3kDa
20 µg/$270; 100 µg/$390
CST3 / Cystatin C Protein - Purified recombinant protein CST3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
13.3 kDa
20 µg/$1,107
CST3 / Cystatin C Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
CST3 / Cystatin C Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
E. coli
10His, N-terminus + Myc, C-terminus
20.4 kDa
20 µg/$405; 1 mg/$1,679; 100 µg/$598
CST3 / Cystatin C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
15.8 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
14.4 kDa
10 µg/$317; 50 µg/$524
CST3 / Cystatin C Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
15.8 kDa
20 µg/$150
CST3 / Cystatin C Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Select
Human
None
1 mg/$777; 10 mg/$4,668
CST3 / Cystatin C Protein
Select
HEK 293 Cells
His, N-Terminal
~15 kDa (20-25 kDa reducing conditions)
10 µg/$289; 50 µg/$360
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.4kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Human Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
14.8 kDa
100 µg/$854; 1 mg/$4,512
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
14.7 kDa
20 µg/$603
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
15 kDa
100 µg/$854
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
16.5 kDa
10 µg/$288; 50 µg/$436
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.4 kDa
10 µg/$317; 50 µg/$524
Select
Mammalian Cells
None
Less than 1.0 EU/µg protein (determined by LAL method).
13.3 kDa
10 µg/$317; 50 µg/$524
Select
E. coli
6His, N-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
16.5kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
14.4kD
10 µg/$321; 50 µg/$534; 500 µg/$1,680; 1 mg/$2,353
CST3 / Cystatin C Protein - Recombinant  Cystatin 3 By SDS-PAGE
Select
E. coli
His-T7
17.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
CST3 / Cystatin C Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
CST3 / Cystatin C Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
15 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
HEK 293 Cells
8His, N-terminus
14.8 kDa
100 µg/$298
Viewing 1-25 of 31 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).