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CHMP2B

charged multivesicular body protein 2B

Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.

Gene Name: charged multivesicular body protein 2B
Synonyms: CHMP2B, ALS17, CHMP2.5, Chromatin-modifying protein 2b, DKFZP564O123, HVps2-2, VPS2-2, VPS2 homolog B, VPS2B, Chromatin modifying protein 2B, DMT1
Target Sequences: NM_014043 NP_054762.2 Q9UQN3

☰ Filters
Antibodies (30)
Proteins (6)
ELISA Kits (1)
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Over-Expression Lysate (2)
Primary (30)
Recombinant (4)
CHMP2B (37)
Human (30)
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rabbit (23)
mouse (6)
sheep (1)
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monoclonal mc (6)
polyclonal pc (24)
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CHMP2B Antibody - Immunohistochemical analysis of CHMP2B staining in human gastric cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
CHMP2B Antibody - CHMP2B / DMT1 antibody Western Blot of Rat Spleen.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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CHMP2B Rabbit anti-Rat Polyclonal (N-Terminus) Antibody
Rat
WB
Unconjugated
100 µl/$424
CHMP2B Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer tissue.
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CHMP2B Antibody - Immunohistochemistry of paraffin-embedded human gastric cancer using CHMP2B antibody at dilution of 1:100 (40x lens).
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
CHMP2B Protein
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E. coli
His
100 µg/$411; 500 µg/$985; 20 µg/$276
CHMP2B Antibody - Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using CHMP2B antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with alpha-tubulin antibody (Red) at 1:2000.
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Human
ICC, IF, WB
Unconjugated
100 µl/$450
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CHMP2B Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$440; 200 µl/$468
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
CHMP2B Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution 1:100
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$294; 100 µl/$360
CHMP2B Antibody - CHMP2B Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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CHMP2B Rabbit anti-Human Polyclonal (aa1-30) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$356; 100 µl/$461
CHMP2B Antibody - Detection of human CHMP2B by immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti- CHMP2B used at a dilution of 1:1,000 (1µg/ml). Detection: DAB. Counterstain: IHC Hematoxylin (blue).
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CHMP2B Rabbit anti-Human Polyclonal (aa163-213) Antibody
Mouse, Human
IHC, WB
Unconjugated
10 µl/$295; 100 µl/$514
CHMP2B Antibody - Western blot analysis of extracts of COLO205 cells using CHMP2B antibody. The lane on the left was treated with blocking peptide.
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CHMP2B Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
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CHMP2B Mouse anti-Human Monoclonal (2H6-1E6) Antibody
Human
ELISA
Unconjugated
100 µg/$705
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CHMP2B Mouse anti-Human Monoclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
100 µl/$904
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CHMP2B Mouse anti-Human Monoclonal (Biotin) Antibody
Human
ELISA
Biotin Conjugated
100 µl/$904
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CHMP2B Mouse anti-Human Monoclonal (PE) Antibody
Human
ELISA
PE Conjugated
100 µl/$904
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CHMP2B Mouse anti-Human Monoclonal (APC) Antibody
Human
ELISA
APC Conjugated
100 µl/$904
Viewing 1-25 of 37 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).