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BAG3 / BAG-3
BCL2-associated athanogene 3
BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
| Gene Name: | BCL2-associated athanogene 3 |
| Synonyms: | BAG3, Bcl-2-associated athanogene 3, Bcl-2-binding protein Bis, BCL2-binding athanogene 3, BIS, BAG-3, CAIR-1, Docking protein cair1, BCL2-associated athanogene 3, Docking protein CAIR-1 |
| Target Sequences: | NM_004281 NP_004272.2 O95817 |
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BAG3 / BAG-3 Goat anti-Human Polyclonal (aa563-575) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$386
Sandwich
96-Well Microplate
Human
0.16 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
BAG3 / BAG-3 Goat anti-Human Polyclonal (aa537-548) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
Yeast
6His, N-terminus
63.7 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa276-294) Antibody
Human, Monkey
IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
50 µl/$386
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa491-506) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa31-62) Antibody
Human
Peptide-ELISA, WB
Unconjugated
200 µl/$393
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa300-350) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa525-575) Antibody
Human
IHC, IHC-P, IP, WB
Unconjugated
100 µl/$485
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa215-264) Antibody
Human
WB
Unconjugated
100 µl/$424
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa215-264) (HRP) Antibody
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Gibbon, Chimpanzee, Human
WB
HRP Conjugated
100 µl/$469
BAG3 / BAG-3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100 µg/$331
E. coli
His-SUMO
77.7 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
BAG3 / BAG-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (380-460 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
BAG3 / BAG-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µl/$334; 100 µl/$397
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa100-561) Antibody
Rat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
BAG3 / BAG-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
BAG3 / BAG-3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
BAG3 / BAG-3 Rabbit anti-Human Polyclonal Antibody
Human
IHC, IP, WB
Unconjugated
50 µl/$393
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Human
IHC, IP, WB
Unconjugated
50 µl/$393
BAG3 / BAG-3 Rabbit anti-Human Polyclonal (aa403-452) Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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