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| Catalog Number | Size | Price |
|---|---|---|
| LS-G145665-10 | 10 µg | $278 |
| LS-G145665-50 | 50 µg | $364 |
| LS-G145665-1 | 1 mg | $1,470 |
Human TNFRSF10B / Killer / DR5 Protein (Recombinant) - LS-G145665
Human TNFRSF10B / Killer / DR5 Protein (Recombinant) - LS-G145665
Description:
TNFRSF10B / Killer / DR5 Protein LS-G145665 is a Recombinant Human TNFRSF10B / Killer / DR5. It is biologically active and is low in endotoxin; Less than 1 EU/µg (determined by LAL method). For Research Use Only
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Description:
TNFRSF10B / Killer / DR5 Protein LS-G145665 is a Recombinant Human TNFRSF10B / Killer / DR5. It is biologically active and is low in endotoxin; Less than 1 EU/µg (determined by LAL method). For Research Use Only
Specifications
Type
Recombinant Protein
Target
TNFRSF10B / Killer / DR5
Synonyms
TNFRSF10B | Cytotoxic TRAIL receptor-2 | CD262 antigen | DR5 | Death receptor 5 | KILLER | TRAIL-R2 | TRICK2B | TRAILR2 | TRICK2A | TRICKB | TRICK2 | CD262 | Fas-like protein | TRAIL receptor 2 | ZTNFR9
Species
Human
Modifications
Unmodified
Conjugations
Unconjugated
Predicted Molecular Weight
14.8 kDa
AA Sequence
ESALITQQDLAPQQRAAPQQKRSSPSEGLCPPGHHISEDGRDCISCKYGQDYSTHWNDLLFCLRCTRCDSGEVELSPCTTTRNTVCQCEEGTFREEDSPEMCRKCRTGCPRGMVKVGDCTPWSDIECVHKES
Source Species
E. coli
Purification
Greater than 97% by SDS-PAGE and HPLC
Usage Summary
A single non-glycosylated polypeptide chain containing 132 amino acids.
Bio-Activity
Fully biologically active when compared to standard. rHusTRAIL-R2 reduced the production of LPS-induced TNF by its ability to neutralize endogenous TRAIL in fresh human PBMC. In this assay, endogenous TRAIL is induced during a 24 hour exposure to LPS (10 ng/mL) but in the presence of rHusTRAIL-R2, TRAIL-induced TNF is suppressed.
Endotoxin
Less than 1 EU/µg (determined by LAL method).
Presentation
Lyophilized from a 0.2 um filtered concentrated solution in PBS, pH 7.4
Reconstitution
Briefly centrifuge prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/ml.
Storage
Store lyophilized at 2°C to 8°C for short term storage. Store lyophilized at -20°C for long term storage. Store reconstituted at 2°C to 8°C for up to 1 week. Aliquot and store reconstituted at -20°C to -70°C. Avoid repeated freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
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Popular TNFRSF10B / Killer / DR5 Proteins
Source:
E. coli
Tag:
6His, N-terminus
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/16/2024
Date Requested: 5/16/2024
