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Catalog Number Size Price
LS-B16514-50 50 µl (1 mg/ml) $460 
KRT8 / CK8 / Cytokeratin 8 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT8 / CK8 / Cytokeratin 8 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT8 / CK8 / Cytokeratin 8 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT8 / CK8 / Cytokeratin 8 Antibody - Western blot analysis of Cytokeratin 8 expression in HeLa (A); mouse brain (B) whole cell lysates.
KRT8 / CK8 / Cytokeratin 8 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT8 / CK8 / Cytokeratin 8 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT8 / CK8 / Cytokeratin 8 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
KRT8 / CK8 / Cytokeratin 8 Antibody - Western blot analysis of Cytokeratin 8 expression in HeLa (A); mouse brain (B) whole cell lysates.
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PathPlus™ Monoclonal Mouse anti‑Human KRT8 / CK8 / Cytokeratin 8 Antibody (IHC, WB) LS‑B16514

PathPlus™ Monoclonal Mouse anti‑Human KRT8 / CK8 / Cytokeratin 8 Antibody (IHC, WB) LS‑B16514

Note: This antibody replaces LS-C413524
Antibody:
KRT8 / CK8 / Cytokeratin 8 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$460
LS-B16514-50
Toll Free North America
(800) 227-6666
For Research Use Only

Overview

Antibody:
KRT8 / CK8 / Cytokeratin 8 Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, WB
Reactivity:
Human, Mouse, Rat
Format:
Unconjugated, Unmodified

Specifications

Description
Cytokeratin 8 (KRT8, CK8) is a Type II intermediate filament chain keratin that is expressed in simple glandular epithelia and the liver. Along with KRT18, KRT8 protects the liver from stress-induced injury and apoptosis. Mutations in this gene have been linked to cryptogenic cirrhosis, rhabdoid tumors, chronic pancreatitis and liver disease. It is a component of nuclear inclusions in rhaboid tumors and Mallory bodies in liver diseases. KRT8 is positive in a variety of cancers. References: Hepatology 2007 46(5):1639; Mod Pathol 2002 15:146; Dig Liver dis 2003 35:416; J Cell Biol 2005 171(6):931
Target
Human KRT8 / CK8 / Cytokeratin 8
Synonyms
KRT8 | CARD2 | CK-8 | CYK8 | Cytokeratin-8 | CK8 | K2C8 | K8 | KO | Keratin-8 | Type-II keratin Kb8 | Cytokeratin 8 | Keratin 8
Host
Mouse
Reactivity
Human, Mouse, Rat (tested or 100% immunogen sequence identity)
Clonality
Monoclonal
Conjugations
Unconjugated
Purification
Purified
Modifications
Unmodified
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence of human Cytokeratin 8.
Specificity
Recognizes endogenous levels of Cytokeratin 8 protein.
Applications
  • IHC - Paraffin (1:100)
  • Western blot (1:2000 - 1:5000)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, pH 7.3, 0.01% Sodium Azide, 30% Glycerol
Storage
Aliquot and store at -20°C for 1 year. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About KRT8 / CK8 / Cytokeratin 8
P05787 NM_002273 NP_002264.1

Validation

KRT8 / CK8 / Cytokeratin 8 Antibody - Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE)

KRT8 / CK8 / Cytokeratin 8 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

KRT8 / CK8 / Cytokeratin 8 Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

LSBio Ratings

PathPlus™ KRT8 / CK8 / Cytokeratin 8 Antibody for IHC, WB/Western LS-B16514 has an LSBio Rating of
Laboratory Validation Score (5)

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Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/31/2024