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| Catalog Number | Size | Price |
|---|---|---|
| LS-C498459-50 | 50 µg | $294 |
| LS-C498459-100 | 100 µg | $360 |
Polyclonal Rabbit anti‑Human PTBP1 Antibody (IHC) LS‑C498459
Polyclonal Rabbit anti‑Human PTBP1 Antibody (IHC) LS‑C498459
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
PTBP1 antibody LS-C498459 is an unconjugated rabbit polyclonal antibody to human PTBP1. Validated for ELISA and IHC.
Target
Human PTBP1
Synonyms
PTBP1 | HnRNP I | HNRNPI | HNRPI | PTB | PPTB | PTB2 | PTB4 | RNA-binding protein | HNRNP-I | PTB-1 | PTB-T | PTB3
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Recombinant Human Polypyrimidine tract-binding protein 1 protein (135-292AA)
Specificity
Plays a role in pre-mRNA splicing and in the regulation of alternative splicing events. Activates exon skipping of its own pre-mRNA during muscle cell differentiation. Binds to the polypyrimidine tract of introns. May promote RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA. May promote the binding of U2 snRNP to pre-mRNA. Cooperates with RAVER1 to modulate switching between mutually exclusive exons during maturation of the TPM1 pre-mRNA. Represses the splicing of MAPT/Tau exon 10 (PubMed:15009664). In case of infection by picornaviruses, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:21518806).
Applications
- IHC
- ELISA
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol.
Storage
Short term: -20°C; Long term: -80°C; Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About PTBP1
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat, Rodent
Applications:
Immunofluorescence, Western blot, Immunoprecipitation
Species:
Human, Monkey, Mouse, Rat, Bovine, Hamster, Pig
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Source:
E. coli
Tag:
His, N-Terminal
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/5/2024
Date Requested: 5/5/2024
