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| Catalog Number | Size | Price |
|---|---|---|
| LS-C116360-100 | 100 µl (0.5 mg/ml) | $424 |
Polyclonal Rabbit anti‑Human SUV39H2 Antibody (aa287‑336, WB) LS‑C116360
Polyclonal Rabbit anti‑Human SUV39H2 Antibody (aa287‑336, WB) LS‑C116360
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Specifications
Description
SUV39H2 antibody LS-C116360 is an unconjugated rabbit polyclonal antibody to human SUV39H2 (aa287-336). Validated for WB. Cited in 4 publications.
Target
Human SUV39H2
Synonyms
SUV39H2 | H3-K9-HMTase 2 | Lysine N-methyltransferase 1B | Su(var)3-9 homolog 2 | KMT1B
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic peptide from internal of human SUV39H2 (D3DRT4, NP_078946 aa 287-336). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Mouse, Rabbit, Horse, Guinea pig (100%); Marmoset, Rat, Dog, Bovine, Pig, Xenopus (92%); Elephant, Bat, Opossum, Platypus (85%).
Epitope
aa287-336
Specificity
Human SUV39H2
Applications
- Western blot (0.2 - 1 µg/ml)
Usage
Western Blot: Suggested dilution at 1 ug/ml in 5% skim milk / PBS buffer, and HRP conjugated anti-Rabbit IgG should be diluted in 1: 50,000 - 100,000 as secondary antibody.
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About SUV39H2
LSBio Ratings
SUV39H2 Antibody (aa287-336) for WB/Western LS-C116360 has an LSBio Rating of
Publications (4.3)
Learn more about The LSBio Ratings Algorithm
Publications (4)
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation. Velazquez Camacho O, Galan C, Swist-Rosowska K, Ching R, Gamalinda M, Karabiber F, De La Rosa-Velazquez I, Engist B, Koschorz B, Shukeir N, Onishi-Seebacher M, van de Nobelen S, Jenuwein T. eLife. 2017 6: (WB; Mouse)
Complete loss of H3K9 methylation dissolves mouse heterochromatin organization. Thomas Montavon, Nicholas Shukeir, Galina Erikson, Bettina Engist, Megumi Onishi-Seebacher, Devon Ryan, Yaarub Musa, Gerhard Mittler, Alexandra Graff Meyer, Christel Genoud, Thomas Jenuwein. Nature communications. 2021 July;12:4359.
Regulation of mammalian 3D genome organization and histone H3K9 dimethylation by H3K9 methyltransferases. Kei Fukuda, Chikako Shimura, Hisashi Miura, Akie Tanigawa, Takehiro Suzuki, Naoshi Dohmae, Ichiro Hiratani, Yoichi Shinkai. Communications biology. 2021 May;4:571.
HP1 maintains protein stability of H3K9 methyltransferases and demethylases. Ryo Maeda, Makoto Tachibana. EMBO reports. 2022 April;23:e53581.
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Featured Products
Species:
Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC - Paraffin, ICC, Immunofluorescence, Western blot
Reactivity:
Rat
Range:
0.156-10 ng/ml
Species:
Human, Mouse
Applications:
IHC, Western blot, Flow Cytometry, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 4/25/2024
Date Requested: 4/25/2024
