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Anti-PSEN2 / Presenilin 2 Antibody (aa319-334) LS-C172226

Note: This antibody replaces LS-C312534

Ordering

Wt. Vol. Conc. Price
100 µg - - $295
Inquire for larger quantities

LSBio (Direct) LSBio (Direct)
206-374-1102
866-206-6909
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Most Popular PSEN2 / Presenilin 2 Antibodies

Anti-PSEN2 / Presenilin 2 Antibody (aa32-65) LS-C344240
Rabbit Polyclonal to Human PSEN2 / Presenilin 2
Human
Western blot, Flow Cytometry
Unconjugated
Western blot Image

100% Guaranteed 100% Guaranteed
Rabbit Polyclonal to Human PSEN2 / Presenilin 2
Human, Rat
IHC - Paraffin, IHC - Frozen, Western blot (applications tested for the base form of this product only)
Unconjugated

Details

Human PSEN2 / Presenilin 2
Rabbit
Human, Rat (tested or 100% immunogen sequence identity)
Polyclonal
Unconjugated. Also available conjugated with Magnetic beads.
Immunoaffinity purified
Unmodified

Applications

  • IHC - Paraffin
  • IHC - Frozen
  • Western blot
  • (applications tested for the base form of this product only)

Specificity and Use

PSEN2 / Presenilin 2 antibody was raised against synthetic peptide corresponding to a sequence at the middle region of human Presenilin-2 (319-334 aa), identical to the related mouse and rat sequence.
aa319-334
Human, rat No cross reactivity with other proteins.

Packaging

5 mg BSA, 0.9 mg sodium chloride, 0.2 mg sodium phosphate, 0.05 mg Thimerosal, 0.05 mg sodium azide
Short term +4°C; Long term -20°C
For research use only.

About PSEN2 / Presenilin 2

P49810 NM_000447 NP_000438.2

PSEN2 Antibody, AD3LP Antibody, AD4 Antibody, AD5 Antibody, AD3L Antibody, CMD1V Antibody, PS-2 Antibody, PSNL2 Antibody, PS2 Antibody, STM2 Antibody, Presenilin 2 Antibody, STM-2 Antibody, E5-1 Antibody, Presenilin-2 Antibody

Alzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease-linked mutations result in increased production of the longer form of amyloid-beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma-secretase, an enzyme that cleaves APP.

Immunohistochemistry

Immunohistochemistry
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Western blot

Western blot
This image was taken for the unconjugated form of this product. Other forms have not been tested.

Requested From: United States
Date Requested: 12/6/2016

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