The Immunohistochemistry Antibody Company
|Human (tested or 100% immunogen sequence identity)|
|IHC - Paraffin, IHC - Frozen|
|NOTCH1 antibody was raised against synthetic peptide corresponding to aa from human NOTCH1 at C-terminal (KLH).|
|PBS, 0.05% sodium azide, 0.2% bovine|
|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at 12 months.|
|For research use only.|
NOTCH1 Antibody, Notch 1 Antibody, TAN1 AntibodyFunctions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs.