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KCNJ11 / Kir6.2

potassium inwardly-rectifying channel, subfamily J, member 11

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.

Gene Name: potassium inwardly-rectifying channel, subfamily J, member 11
Family/Subfamily: Ion Channel , Potassium channel - inward-rectifying
Synonyms: KCNJ11, BIR, IKATP, HHF2, PHHI, TNDM3, Beta-cell KATP channel, KIR6.2
Target Sequences: NM_000525 NP_000516.3 Q14654

☰ Filters
Antibodies (39)
ELISA Kits (2)
Proteins (2)
Cell-Based (1)
Cell-Based Phosphorylation (1)
Primary (39)
Recombinant (2)
KCNJ11 / Kir6.2 (43)
Human (41)
Mouse (34)
Rat (12)
Bat (4)
Bovine (5)
Chimpanzee (3)
Dog (3)
Gibbon (3)
Guinea pig (4)
Horse (3)
Monkey (4)
Pig (5)
Rabbit (6)
IHC (14)
IHC-P (5)
WB (33)
Flo (7)
ELISA (23)
ICC (2)
IF (12)
Peptide-ELISA (5)
rabbit (37)
goat (2)
Product Group
IHCPlus (3)
IgG (27)
polyclonal pc (39)
96-Well Microplate (2)
APC Conjugated (2)
Azide-free (2)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (2)
Unconjugated (23)
aa1-27 (7)
aa1-30 (7)
aa121-170 (4)
160-240 aa (2)
pThr224 (2)
Internal (1)
Val220 (1)
aa18-30 (1)
aa190-239 (1)
aa30-42 (1)
p224 (1)
No (43)
Adherent Cell Cultures (2)
GST (1)
GST, N-terminus (1)
Human (2)
Wheat Germ Extract (2)
Purified (1)
KCNJ11 / Kir6.2 Antibody - Anti-KCNJ11 / Kir6.2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:100.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa190-239) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$440
KCNJ11 / Kir6.2 Antibody - Anti-KCNJ11 / Kir6.2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
Select
KCNJ11 / Kir6.2 Goat anti-Human Polyclonal (aa30-42) Antibody
Rabbit, Mouse, Guinea pig, Rat, Bat, Human, Monkey
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
KCNJ11 / Kir6.2 Antibody - Anti-KCNJ11 / Kir6.2 antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 75 ug/ml.
Select
KCNJ11 / Kir6.2 Goat anti-Human Polyclonal (aa18-30) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
KCNJ11 / Kir6.2 Antibody - Western blot of KIR6.2 antibody
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (160-240 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KCNJ11 / Kir6.2 Antibody - Western blot of KCNJ11 Antibody in mouse stomach tissue lysates (35 ug/lane). KCNJ11 (arrow) was detected using the purified antibody.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
Flo, WB
Unconjugated
400 µl/$393
KCNJ11 / Kir6.2 Antibody - Immunohistochemical analysis of Kir6.2 (pT224) staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Human
ICC, IF, IHC, WB
Unconjugated
30 µl/$263; 100 µl/$315; 200 µl/$379
KCNJ11 / Kir6.2 Antibody - Immunohistochemical analysis of Kir6.2 staining in human brain cortex formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (Internal) Antibody
Rabbit, Mouse, Bovine, Rat, Pig, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
KCNJ11 / Kir6.2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using Kir6.2 (Ab-224) antibody.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (p224) Antibody
Mouse, Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$357
KCNJ11 / Kir6.2 Antibody - 1:100 staining rat brain tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (160-240 aa) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KCNJ11 / Kir6.2 Antibody - IHC of Kir6.2 (V220) pAb in paraffin-embedded human brain tissue.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (Val220) Antibody
Mouse, Human
IF, IHC, IHC-P, WB
Unconjugated
50 µl/$321; 100 µl/$403
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
50 µg/$305; 100 µg/$357
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$331
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) Antibody
Mouse, Human
ELISA, Flo, WB
Unconjugated
200 µl/$734
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) (Biotin) Antibody
Mouse, Human
ELISA, Flo, WB
Biotin Conjugated
200 µl/$952
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) (FITC) Antibody
Mouse, Human
ELISA, Flo, WB
FITC Conjugated
200 µl/$952
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) (APC) Antibody
Mouse, Human
ELISA, Flo, WB
APC Conjugated
200 µl/$952
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) (PE) Antibody
Mouse, Human
ELISA, Flo, WB
PE Conjugated
200 µl/$952
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (aa1-30) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, Flo, WB
HRP Conjugated, Azide-free
200 µl/$952
KCNJ11 / Kir6.2 Antibody - P-peptide - + Immunofluorescence analysis of HuvEc cells, using Kir6.2 (Phospho-Thr224) antibody.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (pThr224) Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
KCNJ11 / Kir6.2 Antibody - Immunofluorescence analysis of HUVEC cells, using Kir6.2 (Phospho-Thr224) Antibody. The picture on the right is blocked with the phospho peptide.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal (pThr224) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
Select
KCNJ11 / Kir6.2 Rabbit anti-Mouse Polyclonal (aa1-27) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
KCNJ11 / Kir6.2 Antibody - Immunohistochemistry of paraffin-embedded Human prostate cancer using KCNJ11 Polyclonal Antibody at dilution of 1:40.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
KCNJ11 / Kir6.2 Antibody - Western blot analysis of extracts of various cell lines.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
KCNJ11 / Kir6.2 Antibody - Immunohistochemistry of paraffin-embedded Human brain using KCNJ11 Polyclonal Antibody at dilution of 1:40.
Select
KCNJ11 / Kir6.2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Viewing 1-25 of 43 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).