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Catalog Number Size Price
LS-C188728-0.25 0.25 mg (1 mg/ml) $486 
Antibody

Monoclonal Mouse anti‑Rat ITGAM / CD11b Antibody (clone ED8, IHC) LS‑C188728

Monoclonal Mouse anti‑Rat ITGAM / CD11b Antibody (clone ED8, IHC) LS‑C188728

Antibody:
ITGAM / CD11b Mouse anti-Rat Monoclonal (ED8) Antibody
Application:
IHC-Fr
Reactivity:
Rat
Format:
Unconjugated, Unmodified
Price
Catalog Number
$486
LS-C188728-0.25
Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
ITGAM / CD11b Mouse anti-Rat Monoclonal (ED8) Antibody
Application:
IHC-Fr
Reactivity:
Rat
Format:
Unconjugated, Unmodified

Specifications

Description
CD11b antibody LS-C188728 is an unconjugated mouse monoclonal antibody to rat CD11b (ITGAM). Validated for IHC.
Target
Rat ITGAM / CD11b
Synonyms
ITGAM | Antigen CD11b (p170) | CD11B | CD11b antigen | CR3A | Integrin alpha-M | MAC-1 | MO1A | Neutrophil adherence receptor | MAC1A | SLEB6 | CR-3 alpha chain
Host
Mouse
Reactivity
Rat (tested or 100% immunogen sequence identity)
Clonality
IgG1 Monoclonal
Clone
ED8
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
Rat spleen cell homogenate with FCA.
Specificity
Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
Applications
  • IHC - Frozen
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Failed Applications
  • IHC - Paraffin
Presentation
PBS, 0.09% Sodium Azide
Storage
Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About ITGAM / CD11b
P11215 NM_000632 NP_000623.2

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Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 4/18/2024